The San Francisco 49ers and Atlanta Falcons meet Sunday night at Levi’s Stadium in a game that could shape the NFC playoff picture. San Francisco enters 4-2 and ties at first in the NFC West, while Atlanta sits 3-2 and holds second place in the NFC South. Both teams need a win to maintain their momentum.
The 49ers opened the season with three straight wins before stumbling in two of their last three games, including a 30-19 loss to Tampa Bay in Week 6. Atlanta bounced back from an early loss with a 24-14 upset of Buffalo following their bye week.
San Francisco 49ers at Atlanta Falcons
Game Details
Date: Sunday, October 19, 2025
Time: 8:20 p.m. ET
Location: Levi’s Stadium, Santa Clara, CA
How to Watch
TV: NBC (national)
Live Stream: Peacock
Radio: SiriusXM NFL Radio 88 (national); SiriusXM
Announcers: Mike Tirico (play-by-play), Cris Collinsworth (analyst)
49ers Offense vs. Falcons Defense
San Francisco’s offense has been inconsistent through six games. The 49ers have the 15th-ranked offense in PFSN’s Offense Impact metric with a 76.0 score and a C grade. They average 20.8 points per game while converting 45.35% of third downs.
Mac Jones has thrown for 1,252 yards, but the offensive line has surrendered 13 sacks. The bigger concern is ball security; the 49ers carry a minus-5 turnover margin that’s cost them games. Christian McCaffrey remains the dual-threat centerpiece with 336 rushing yards.
Atlanta’s defense has been one of the league’s better units. The Falcons have the 7th-ranked defense in PFSN’s Defense Impact metric with a 79.1 score and a C+ grade. They allow 20.0 points per game and have limited opponents on money downs.
The pass rush has generated 14 sacks through five games, while the offense has protected Michael Penix Jr. well. Jessie Bates III anchors the secondary with 29 tackles, while Xavier Watts has picked off two passes. Atlanta’s plus-3 turnover margin sets up a key contrast against San Francisco’s giveaway issues.
Falcons Offense vs. 49ers Defense
Atlanta’s offense runs through the ground game. The Falcons have the 16th-ranked offense in PFSN’s Offense Impact metric with a 75.8 score and a C grade. They manage 20.0 points per game and control the clock with a run-first approach.
Michael Penix Jr. has thrown for 1,168 yards as a rookie behind strong protection that’s surrendered just seven sacks. Bijan Robinson leads the rushing attack with 484 yards, while Drake London paces the passing game with 427 receiving yards. The balanced attack keeps defenses honest.
San Francisco’s defense has struggled compared to recent seasons. The 49ers have the 24th-ranked defense in PFSN’s Defense Impact metric with a 70.3 score and a C- grade. The unit allows 21.3 points per game and hasn’t generated consistent pressure.
The pass rush has recorded just seven sacks through six games. Fred Warner leads the team with 51 tackles, but the 49ers miss the havoc that defined their championship runs. Slowing Robinson’s ground attack will be critical to keeping San Francisco in position to win.
The matchup favors Atlanta’s ball-control style against San Francisco’s defensive struggles. The Falcons’ ability to protect the football and dominate possession should exploit the 49ers’ minus-5 turnover margin. San Francisco needs McCaffrey to take over and the defense to create game-changing plays if they want to protect home field and maintain their division lead.

