Indiana vs. Penn State Prediction: Can the Nittany Lions Play College Football Playoff Spoiler in Week 11?

Our Indiana vs. Penn State prediction dives into the details to find out whether the Nittany Lions can play spoiler in the College Football Playoff race.

The Penn State Nittany Lions (3-5, 0-5) host the No. 2 Indiana Hoosiers (6-0, 9-0) at Beaver Stadium on Saturday, November 8, in a Big Ten matchup with significant implications for both sides.

Our Indiana vs. Penn State prediction dives into the details of the matchup with a look at the head-to-head history, exclusive PFSN player and team grades, and a score forecast for the Big Ten matchup.

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Indiana vs. Penn State Details

  • Date: Nov. 8, 2025
  • Game time: 12:00 p.m. ET
  • Location: West Shore Home Field at Beaver Stadium, University Park, PA
  • Predicted Weather at Kick: 55 degrees Fahrenheit
  • How To Watch: FOX

Indiana vs. Penn State Head-to-Head Record

Saturday marks the 28th head-to-head matchup between Indiana and Penn State, a series that began on November 6, 1993, when the Nittany Lions claimed a 38-31 victory. Penn State has dominated the rivalry ever since, holding a commanding 25-2 record against the Hoosiers.

Indiana’s only two wins came in 2013 and 2020, both at home in Bloomington. The teams last met in 2023, with Penn State securing a 33-24 victory at University Park. The Hoosiers enter the game on a three-game losing streak to the Nittany Lions and are looking to change this narrative on Saturday while keeping their undefeated season alive.

Indiana vs. Penn State Grades

PFSN College OFFi

  • Indiana (93.3, A)
  • Penn State (81.3, B-)

PFSN College DEFi

  • Indiana (98.3, A+)
  • Penn State (78.7, C+)

PFSN College OLi

  • Indiana (87.1, B+)
  • Penn State (83.9, B)

PFSN College QBi

  • Fernando Mendoza, Indiana (96.4, A)
  • Drew Allar, Penn State (76.9, C)

PFSN College RBi

  • Roman Hemby, Indiana (76.2, C)
  • Kaytron Allen, Penn State (83.1, B)

PFSN College WRi

  • Omar Cooper Jr., Indiana (83.3, B)
  • Devonte Ross, Penn State (78.2, C+)

PFSN College TEi

  • Riley Nowakowski, Indiana (80.4, B-)
  • Luke Reynolds, Penn State (77.2, C+)

PFSN College EDGEi

  • Stephen Daley, Indiana (79.7, C+)
  • Dani Dennis-Sutton, Penn State (79.9, C+)

PFSN College DTi

  • Tyrique Tucker, Indiana (81.2, B-)
  • Zane Durant, Penn State (75.5, C)

PFSN College LBi

  • Aiden Fisher, Indiana (78.5, C+)
  • Amare Campbell, Penn State (77.3, C+)

PFSN College CBi

  • D’Angelo Ponds, Indiana (91.1, A-)
  • Daryus Dixson, Penn State (82, B-)

PFSN College SAFi

  • Louis Moore, Indiana (88.6, B+)
  • Zakee Wheatley, Penn State (83.5, B)

Indiana vs. Penn State Prediction

Although Penn State may have home-field advantage and a strong history in this series, it means nothing because of Indiana’s dominance this season. The Hoosiers have proven themselves on both sides of the ball, ranking No. 2 offensively in PFSN’s College Offense Impact and No. 1 defensively.

Quarterback Mendoza has been the difference-maker, showing leadership week after week. He has developed chemistry with Omar Cooper Jr. on offense, who continues to be a consistent playmaker for the Hoosiers.

Meanwhile, Penn State’s struggles under interim head coach Smith, combined with the loss of Allar, have the program looking for stability. Their offense has yet to find a rhythm, and facing one of the top defenses in the nation puts them at a major disadvantage.

Prediction: Indiana 30, Penn State 14

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