NFL Week 4 Odds and Betting Trends Against the Spread for Every Game

The NFL Week 4 odds feature a few massive numbers but even more coin flips! What teams can you trust now that we have three weeks of data?

The weather is beginning to cool, and that means we are gearing up for the meat of the season. That’s great news because the more information we have, the sharper our edge is!

The Week 4 odds reflect what the NFL is these days – a competitive league that does have some serious exceptions on both ends of the talent pool. Where should your hard earned dollars be this week? Lets look at the NFL Week 4 spreads, betting lines and trends for every game.

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NFL Week 4 Odds and Betting Trends

All odds are from DraftKings Sportsbook and trends from Inside Edge.

Detroit Lions vs. Green Bay Packers Odds

  • Spread
    Lions -1.5
  • Moneyline
    Lions -115, Packers +100
  • Total
    45.5

The Detroit Lions have not only beaten the Green Bay Packers in each of their past three meetings, but they’ve done so as an underdog on all three occasions (average coverage margin: 9.7 PPG)

No team has been better ATS as an underdog since the start of the 2021 season than the Packers (10-2).

Atlanta Falcons vs. Jacksonville Jaguars Odds

  • Spread
    Jaguars -3
  • Moneyline
    Falcons +124, Jaguars -148
  • Total
    43

Since 2021, unders are 15-9 when the Atlanta Falcons are underdogs (only four teams have a higher hit rate in such spots).

At 1-7 ATS since the start of the 2020 season, the Jacksonville Jaguars are the worst team in the NFL to back when favored.

Miami Dolphins vs. Buffalo Bills Odds

  • Spread
    Bills -3
  • Moneyline
    Dolphins +120, Bills -148
  • Total
    53.5

The Miami Dolphins have played each of their past six road games within seven points (four decided by no more than a FG).

The Buffalo Bills have won seven straight home games over the Dolphins, averaging 35 PPG in the process. In fact, they are 11-1 in their past 12 home games against the ‘Fins, with the one loss coming in overtime (2016).

Denver Broncos vs. Chicago Bears Odds

  • Spread
    Broncos -3
  • Moneyline
    Broncos -162, Bears +136
  • Total
    46

The Denver Broncos haven’t won a road game since Teddy Bridgewater led them to a victory in Dallas in Week 9 of the 2021 season (that will have been 692 days ago when this game kicks off on Sunday).

It’s been over a calendar year since the Chicago Bears won a home game, and they’ve lost each of their past three by more than 15 points.

Baltimore Ravens vs. Cleveland Browns Odds

  • Spread
    Browns -2.5
  • Moneyline
    Ravens +124, Browns -148
  • Total
    41

Under tickets have cashed in seven of the Baltimore Ravens’ past 10 games against a top-10 run defense.

The home team has won four straight in this rivalry (three of which were decided by less than a touchdown).

Cincinnati Bengals vs. Tennessee Titans Odds

  • Spread
    Bengals -2.5
  • Moneyline
    Bengals -130, Titans +114
  • Total
    42.5

Only the New York Giants have a better road ATS mark since the start of last season than the Cincinnati Bengals (7-2).

Overs are 5-2 in the past seven instances in which the Tennessee Titans have been getting a field goal or less.

Los Angeles Rams vs. Indianapolis Colts Odds

  • Spread
    Colts -1.5
  • Moneyline
    Rams +100, Colts -120
  • Total
    46.5

Unders are 10-5 since 2021 when the Los Angeles Rams are coming off of a loss.

The Indianapolis Colts are just 1-6 ATS since the beginning of last season when favored.

Tampa Bay Buccaneers vs. New Orleans Saints Odds

  • Spread
    Saints -3.5
  • Moneyline
    Buccaneers +142, Saints -170
  • Total
    39

The Tampa Bay Buccaneers lost on Monday night and are a league-worst 2-8 ATS following a loss since the beginning of 2021.

The New Orleans Saints lit up the Bucs for 36 points on Halloween of 2021 — we haven’t seen a game between these two reach 35 points since.

Washington Commanders vs. Philadelphia Eagles Odds

  • Spread
    Eagles -8
  • Moneyline
    Commanders +300, Eagles -34\80
  • Total
    44.5

The Washington Commanders are 4-9 ATS when facing a top-10 offense since 2021 (30.8% cover rate).

Overs are 13-5 at Philadelphia since the start of 2021, the highest hit rate in the NFL over that stretch.

Minnesota Vikings vs. Carolina Panthers Odds

  • Spread
    Vikings -3.5
  • Moneyline
    Vikings -185, Panthers +154
  • Total
    45.5

Overs are 20-4 in Minnesota Vikings games following a loss since 2020.

Overs are 9-2 since the beginning of 2021 when the Carolina Panthers take on a top-10 passing offense, a box the Vikings check with Kirk Cousins pacing for over 6,000 yards.

MORE: Early NFL Week 4 Predictions and Picks Against the Spread

Pittsburgh Steelers vs. Houston Texans Odds

  • Spread
    Steelers -3
  • Moneyline
    Steelers -162, Texans +136
  • Total
    42

Unders are 8-4 over the past 12 games in which the Pittsburgh Steelers have been favored.

The Houston Texans are a league-worst 3-10 ATS in the game following a win since 2020.

Las Vegas Raiders vs. Los Angeles Chargers Odds

  • Spread
    Chargers -6
  • Moneyline
    Raiders +205, Chargers -250
  • Total
    48

Overs are 7-3 since 2021 when the Las Vegas Raiders are getting at least four points.

The home team has won four straight in this series and averaged 27.8 points over the past six meetings.

New England Patriots vs. Dallas Cowboys Odds

  • Spread
    Cowboys -7
  • Moneyline
    Patriots +230, Cowboys -285
  • Total
    43.5

The New England Patriots are 3-7 ATS since the beginning of 2021 when opposing a top-10 run offense.

The Dallas Cowboys are a league-best 8-1 ATS following a loss since the beginning of the 2021 season.

Arizona Cardinals vs. San Francisco 49ers Odds

  • Spread
    49ers -14
  • Moneyline
    Cardinals +625, 49ers -900
  • Total
    43.5

Overs have hit at a 69.2% rate since 2021 when the Arizona Cardinals face a top-10 offense.

The San Francisco 49ers are the best ATS home team since the beginning of 2022 with an 80% cover rate (only two other teams are even above 60%).

Kansas City Chiefs vs. New York Jets Odds

  • Spread
    Chiefs -9.5
  • Moneyline
    Chiefs -500, Jets +380
  • Total
    42.5

Overs are 12-6 over the past two-plus seasons when the Kansas City Chiefs play on the road.

Under tickets have come through in seven of the New York Jets’ past nine games against a top-10 pass offense.

Seattle Seahawks vs. New York Giants Odds

  • Spread
    Seahawks -1.5
  • Moneyline
    Seahawks -120, Giants +102
  • Total
    45

Since 2021, the Seattle Seahawks have covered 12 games as an underdog and have won 10 of them outright.

Only the Commanders have seen a higher percentage of home games come in under the total since the beginning of 2021 than the Giants (72.2%).

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