The Divisional Round shifts to primetime in Seattle, where the top-seeded Seahawks host the San Francisco 49ers. Both teams arrive with late-week injury designations that affect key positions, including linebacker availability for the 49ers and quarterback status for the Seahawks.
Official inactives will post approximately 90 minutes before kickoff, finalizing game-day participation for listed questionables and confirming any elevations. The matchup emphasizes early-down execution, field position, and special teams in a cool, loud environment, with run defense and perimeter timing central to both sides. As with all playoff games, personnel clarity close to kickoff will shape sub-packages and rotations across the line and secondary.
NFL Inactives List for 49ers vs. Seahawks
While Sam Darnold is playing tonight, the 49ers will not have Fred Warner. The star linebacker practiced this past week, but ultimately was ruled out. According to PFSN’s Defense Impact Metric, San Francisco’s defense is ranked 26th in the league, and Robert Saleh will have to pull off another miracle to keep the team’s season alive.
Here are the confirmed inactives for tonight’s game:
San Francisco 49ers
- LB Fred Warner
- S Ji’Ayir Brown
- RB Isaac Guerendo
- DT Kevin Givens
- DT Sebastian Valdez
- T Brandon Parker
- WR Jordan Watkins
- DE Robert Beal
Seattle Seahawks
- OL Josh Jones
- LB Chazz Surratt
- QB Jalen Milroe
- OL Mason Richman
- OL Bryce Cabeldue
- DE Rylie Mills
- LB Jared Ivey
Starters for 49ers vs. Seahawks
San Francisco 49ers
- QB Brock Purdy
- RB Christian McCaffrey
- WR1 Ricky Pearsall
- WR2 Jauan Jennings
- FB Kyle Juszczyk
- TE Jake Tonges
- LT Trent Williams
- LG Spencer Burford
- C Jake Brendel
- RG Dominick Puni
- RT Colton McKivitz
Defense:
- LDT Jordan Elliot
- RDT Kalia Davis
- LDE Bryce Huff
- RDE Sam Okuayinonu
- SLB Luke Gifford
- WLB Dee Winters
- MLB Eric Kendricks
- LCB Renardo Green
- RCB Deommodore Lenoir
- FS Malik Mustapha
- SS Jason Pinnock
Special Teams:
- LS Jon Weeks
- H Thomas Morstead
- K-FG Eddy Pineiro
- K-KO Eddy Pineiro
- P Thomas Morstead
- KR Skyy Moore
- PR Skyy Moore
Seattle Seahawks
- QB Sam Darnold
- RB Kenneth Walker III
- WR1 Jaxon Smith-Njigba
- WR2 Rashid Shaheed
- FB Robbie Ouzts
- TE AJ Barner
- LT Charles Cross
- LG Grey Zabel
- C Olu Oluwatimi
- RG Anthony Bradford
- RT Abraham Lucas
Defense:
- NT Byron Murphy II
- DT Brandon Pili
- DE Leonard Williams
- LOLB DeMarcus Lawrence
- ROLB Uchenna Nwosu
- LILB Drake Thomas
- RILB Ernest Jones IV
- RCB Josh Jobe
- LCB Devon Witherspoon
- FS Coby Bryant
- SS Julian Love
Special Teams:
- LS Chris Stoll
- H Michael Dickson
- K-FG Jason Myers
- K-KO Jason Myers
- P Michael Dickson
- KR Rashid Shaheed
- PR Rashid Shaheed
The 49ers’ offense hinges on timing and motion to create intermediate windows for Brock Purdy, with Christian McCaffrey’s touches balancing formations and tempo. With linebackers and safeties listed on the injury report affecting rotations, defensive communication and tackling at the catch point are vital against Seattle’s run-action and vertical shots.
The Seahawks aim to leverage Kenneth Walker III and play-action to Jaxon Smith-Njigba, while an active front led by Leonard Williams and Uchenna Nwosu compresses pockets. Special teams and hidden yards matter in Seattle, with Michael Dickson’s directional punting and Jason Myers’ range influencing field position.
Inactives will clarify the quarterback status for Seattle and confirm San Francisco’s perimeter usage, shaping early scripts and third-down packages. Expect disciplined run fits, limited explosives, and red-zone efficiency to decide margins in a divisional matchup defined by crowd noise, situational execution, and clean operations.
