The San Francisco 49ers visit the Philadelphia Eagles in a marquee Wild Card matchup featuring two elite rosters with contrasting recent form and overlapping vulnerabilities. The 49ers’ offense, powered by Brock Purdy and Christian McCaffrey, meets an Eagles defense that has tightened situationally but allowed consistent rushing production, while Philadelphia’s Saquon Barkley and Jalen Hurts face a 49ers front that was stressed by the run in Week 18.
Weather, crowd noise, and early-down success will shape the tempo and field position, and special teams execution is likely to matter in a game where hidden yards can tilt the momentum. The official game-day inactives post is released approximately 90 minutes before kickoff, finalizing availability for multiple starters on both sides and confirming late-week questionables that influence trench and perimeter matchups.
Inactive List for 49ers vs. Eagles
Both Lane Johnson and Ricky Pearsall were listed as questionable for the Wild Card round. Before the game, it was revealed that Johnson is trending towards not playing, and was eventually ruled out. Similarly, Pearsall is also not available for today’s game.
Here are the confirmed inactives for today’s game:
San Francisco 49ers
- WR Ricky Pearsall
- LB Luke Gifford
- LB Dee Winters
- RB Isaac Guerendo
- DT Kevin Givens
- CB Chase Lucas
- WR Jordan Watkins
Philadelphia Eagles
- OL Brett Toth
- OT Lane Johnson
- QB Sam Howell
- RB A.J. Dillon
- CB Jakorian Bennett
- OLB Joshua Uche
- DL TY Robinson
Starters for 49ers vs. Eagles
San Francisco 49ers
Offense:
- QB Brock Purdy
- RB Christian McCaffrey
- WR1 Kendrick Bourne
- WR2 Jauan Jennings
- FB Kyle Juszczyk
- TE George Kittle
- LT Trent Williams
- LG Spencer Burford
- C Jake Brendel
- RG Dominick Puni
- RT Colton McKivitz
Defense:
- LDT Jordan Elliot
- RDT Kalia Davis
- LDE Bryce Huff
- RDE Sam Okuayinonu
- SLB Luke Gifford
- WLB Dee Winters
- MLB Eric Kendricks
- LCB Renardo Green
- RCB Deommodore Lenoir
- FS Malik Mustapha
- SS Ji’Ayir Brown
Special Teams:
- LS Jon Weeks
- H Thomas Morstead
- K-FG Eddy Pineiro
- K-KO Eddy Pineiro
- P Thomas Morstead
- KR Skyy Moore
- PR Skyy Moore
Philadelphia Eagles
Offense:
- QB Jalen Hurts
- RB Saquon Barkley
- WR1 A.J. Brown
- WR2 DeVonta Smith
- WR3 Jahan Dotson
- TE Dallas Goedert
- LT Jordan Mailata
- LG Landon Dickerson
- C Cam Jurgens
- RG Tyler Steen
- RT Cameron Williams
Defense:
- NT Jordan Davis
- DT Jalen Carter
- DE Moro Ojomo
- LOLB Nolan Smith Jr.
- ROLB Jaelan Phillips
- LILB Zack Baun
- RILB Nakobe Dean
- LCB Quinyon Mitchell
- RCB Adoree’ Jackson
- FS Reed Blankenship
- SS Sydney Brown
Special teams:
- LS Charley Hughlett
- H Braden Mann
- K-FG Jake Elliott
- K-KO Jake Elliott
- P Braden Mann
- KR Will Shipley
- PR Jahan Dotson
Run defense and tailback impact loom as defining variables. San Francisco allowed 4.3 yards per rush in the regular season and was gashed in Week 18, while Philadelphia’s defense yielded 124.4 rush yards per game, inviting McCaffrey and Barkley to drive efficiency and set up play‑action.
For the 49ers, Purdy’s timing and intermediate windows to Kittle and perimeter threats require protection continuity at tackle and guard. According to PFSN’s Offense Impact Metric, San Francisco has the league’s fourth-ranked offense coming into the playoffs.
For the Eagles, Hurts benefits from early‑down rhythm, Barkley’s balance, and vertical stress from Brown and Smith. Explosives prevention, red‑zone finishing, turnover margin, and special teams precision are likely to determine the margin.
The questionables at tackle, edge, and receiver for both teams will finalize with inactives, shaping personnel groupings and sub‑packages at the line of scrimmage and in nickel. Expect both staff to script early series to avoid predictable longs and leverage motion to identify coverage tells.
