With the 2025 NFL season about to kick off, all eyes are on the Los Angeles Rams and, more specifically, their star quarterback, Matthew Stafford. At 37 and heading into his 17th season, Stafford is coming off a lingering back injury that kept him out of all the preseason games.
Naturally, fans and analysts alike are worried: can he stay healthy and perform at a high level for a full NFL season?
Matthew Stafford Expected to Start Sunday Versus Houston Texans
The good news for the Rams is that Stafford is expected to start Sunday’s season opener against the Houston Texans. Head coach Sean McVay told reporters that Stafford is ready to lead the team onto the field despite missing much of training camp.
While it’s reassuring that he’ll play, questions remain about just how much his back will affect him during the season and how the coaching staff will manage his workload to keep him healthy.
Rams HC Sean McVay told reporters that QB Matthew Stafford, who missed much of camp with a back injury, is expected to start Sunday’s opener against the Texans. pic.twitter.com/PJOaZTepPn
— Adam Schefter (@AdamSchefter) September 1, 2025
Stafford has been the heart of the Rams’ offense since joining the team, and his leadership is critical as Los Angeles looks to build on last year’s 10-win season and Divisional Round playoff appearance. Analysts see the Rams as strong NFC contenders again this year, with many predicting double-digit wins and even a shot at the Super Bowl.
But all those hopes hinge on Stafford staying on the field and performing at his usual level.
Health is a Concern, Rams Ready to Embark on 2025 Season
The Rams haven’t left their quarterback to carry the load alone. They’ve strengthened their roster in key areas, including the offensive line and skill positions, to support Stafford and give him the best chance to succeed. Still, there’s no hiding the fact that Stafford’s back is a concern, and his health will be closely monitored throughout the season.
Read More: Matthew Stafford Injury Update: Latest on the Rams QB and How Long He’ll Be Sidelined
Fans are relieved that Stafford will play in Week 1, but uncertainty remains. Every game and every play is a focal point because the Rams’ chances of winning the Super Bowl are closely linked to the health of their veteran quarterback.
As the season opener approaches, the focus will be on Stafford: Can he lead the Rams through a challenging schedule while staying healthy? For now, fans can breathe a little easier knowing he’ll take the field, but the bigger question, how the rest of the season unfolds with him under center, remains wide open.

