Brock Purdy Fantasy Hub: Week 16 Injury Update, Start ‘Em/Sit ‘Em Advice, Points Projection, and Weather Impact

Here's this week's fantasy football outlook for Brock Purdy, including injury updates, start-sit advice, points projection, and weather impact.

The San Francisco 49ers will visit the Indianapolis Colts in Week 16. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, specifically regarding QB Brock Purdy.

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Is Purdy Playing in Week 16?

Purdy is not on the injury report and barring a surprise, he is expected to play.

We’ll continue to monitor the 49ers’ injury report leading up to kickoff for any changes. You can also visit and bookmark our Fantasy News Tracker for the latest updates.

Should You Start or Sit Purdy in Week 16?

Brock Purdy handled his business against the undermanned Titans (23-of-30 for 295 yards and three touchdowns), funneling the three-quarters of his looks to three players, routinely taking advantage of mismatches.

He did everything he was asked to and even added 44 rushing yards for good measure (43 rush yards in his first five starts this season). Purdy has completed over 70% of his passes in three of his past four games, and this was the second time he proved capable of taking advantage of a great matchup.

This Colts defense isn’t one to fear, and with his primary playmakers healthy, Purdy is to be viewed as a high-floor play that can help a strong team that just lost Patrick Mahomes. Or maybe on a competitive team that isn’t loving the idea of playing Lamar Jackson against the Patriots.

Asking him to break the slate with a huge game isn’t wise, but 18-22 fantasy points on Monday night with your matchup in the balance can hold value.

Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.

Purdy’s Fantasy Points Projection in Week 16

Purdy is projected to score 19.3 fantasy points in PPR formats.

We project Purdy to throw for 259 yards and 1.8 passing touchdowns with 0.7 interceptions. Purdy could also add 12 rushing yards and 0.2 rushing touchdowns on the ground.

Check out the free PFSN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.

Week 16 Weather Impact: 49ers at Colts

Since the Colts play in a dome, there is no weather impact for this Week 16 matchup. Temperatures will be a comfortable 72 degrees Fahrenheit with no wind.

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