The Kansas City Chiefs will face the Houston Texans in Week 16. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, especially regarding WR DeAndre Hopkins.
Is DeAndre Hopkins Playing in Week 16?
Hopkins is not listed on the injury report this week, so barring any setbacks, he is on track to play this weekend.
We’ll continue to monitor the Chiefs’ injury report. You can also visit and bookmark our NFL Injury Tracker and Fantasy News Tracker for the latest updates.
Should You Start or Sit DeAndre Hopkins in Week 16?
If you’re of a certain age, the name “DeAndre Hopkins” holds theoretical value, but that’s about it for the fantasy playoffs.
Patrick Mahomes has been under center for the past two weeks and yet Hopkins has turned 15 targets into just 78 yards, a level of efficiency that is troubling on many levels. The raw volume is good to see (one target every 3.3 routes in those two games), but if that falls off the table, a truly low floor — with Mahomes active — presents itself.
Without Mahomes?
The fact is, we don’t know what “without Mahomes” looks like. What we do know is that this team wasn’t relying on its passing attack to put it in position for the AFC’s top seed with one of the best QBs in the history of the earth on the roster … is Andy Reid just waiting for Carson Wentz to unleash things?
I doubt it.
I didn’t think we’d be looking at playoff decisions where I’d pick Jalen McMillan over Hopkins, but that’s where I’m at.
Are you looking for start/sit advice for other players in your lineup? Read our Week 16 Fantasy Start-Sit Advice Cheat Sheet for every fantasy-relevant player in every game.
DeAndre Hopkins’ Fantasy Points Projection in Week 16
As of Saturday morning, Hopkins is projected to score 12.5 fantasy points in PPR formats. This includes 4.4 receptions for 54.7 yards and 0.4 touchdowns.
Check out the free PFN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.
PFN Insight on the Bills' Defense
After finishing as a top-seven defense in each of the last three seasons, the Bills finished 18th during the regular season. That's not the biggest surprise given that this was largely billed as a rebuilding season for this unit.
Buffalo was a boom-or-bust defense in the Divisional Round vs. Baltimore, and there were just enough highs to escape with the win. In addition to the three takeaways, the Bills also generated their second-highest non-blitz pressure rate (42.9%) this season. The only higher rate was in the Wild Card win over the Broncos (50%).
This wasn't a particularly efficient defensive performance, as reflected in the final Defense+ grade of 69.9 (D+). Despite some run stuffs, the Bills had their worst rushing defense success rate all season (44%) and were fortunate the game script didn't allow the Ravens to lean more heavily on their run game.
Still, the Bills' offense is operating at such a high level that the bar to clear for the defense is lower than it would be on nearly any other team. Buffalo met that threshold with a few big plays against the Ravens. Those could be tougher to generate against a Chiefs offense that has gone eight straight games without a turnover, but it may be all the Bills need to finally conquer Kansas City.
For more insight on all other team defenses, head to our PFN Defense+ Metric Analysis.
DeAndre Hopkins’ Fantasy Ranking
Our Weekly Consensus PPR Rankings are below — both positional and overall. They were last updated at 11:45 PM ET on Saturday, January 25.
Conference Championship WR PPR Rankings
1) A.J. Brown | PHI (vs. WAS)
2) Terry McLaurin | WAS (at PHI)
3) DeVonta Smith | PHI (vs. WAS)
4) Khalil Shakir | BUF (at KC)
5) Xavier Worthy | KC (vs. BUF)
6) Hollywood Brown | KC (vs. BUF)
7) DeAndre Hopkins | KC (vs. BUF)
8) Keon Coleman | BUF (at KC)
9) Dyami Brown | WAS (at PHI)
10) Mack Hollins | BUF (at KC)
11) Amari Cooper | BUF (at KC)
12) Curtis Samuel | BUF (at KC)
13) Olamide Zaccheaus | WAS (at PHI)
14) JuJu Smith-Schuster | KC (vs. BUF)
15) Jahan Dotson | PHI (vs. WAS)
16) Jamison Crowder | WAS (at PHI)
17) Luke McCaffrey | WAS (at PHI)
18) Justin Watson | KC (vs. BUF)
19) Johnny Wilson | PHI (vs. WAS)
20) Parris Campbell | PHI (vs. WAS)
21) Nikko Remigio | KC (vs. BUF)
22) Ainias Smith | PHI (vs. WAS)
Bills at Chiefs Trends and Insights
Buffalo Bills
Team: The Bills lost four road games during the regular season — only four Super Bowl champions in the 2000s have done that (2018 Patriots, 2012 Ravens, 2010 Packers, and 2006 Colts).
QB: Five times has a QB had four games in a season (playoffs included) with multiple rush touchdowns and 20 pass attempts.
- 2021 Jalen Hurts
- 2022 Jalen Hurts
- 2023 Jalen Hurts
- 2023 Josh Allen
- 2024 Josh Allen
No player has had five such games in a season.
Offense: The Bills have scored on at least 55% of their possessions six times this season, four of which have come against playoff teams.
Defense: Buffalo allowed Baltimore to pick up 70% of their third downs. That’s the fourth-highest rate the Bills have allowed in the 2000s and is their highest in a winning effort.
Fantasy: Allen has completed over 72% of his passes in both playoff wins – he had three such games during the regular season.
Betting: Overs are 5-2 in Buffalo’s past seven games, cashing last week by half a point with Baltimore's final touchdown.
Kansas City Chiefs
Team: Christmas Day 2023 was the date of Kansas City’s last home loss – each of their past six Arrowhead games have been decided by a single possession.
QB: Patrick Mahomes has thrown a total of three touchdown passes in his last two Championship games (3.7% of his attempts) after throwing three in each of his first four appearances (8.4%).
Offense: Saturday was the 10th time this season in which the Chiefs scored on at least half of their possessions (five-of-nine against Houston).
Defense: Opponents have picked up at least half of their third downs in four straight games against the Chiefs (Texans: 10-of-17).
Fantasy: In the last two games in which their starters have been extended, the Chiefs have managed to turn 42 carries into just 119 yards (2.83 yards per carry).
Betting: By taking an intentional safety at the end of their win over the Texans, the Chiefs snapped their six-game playoff cover streak.
