Cowboys vs. Cardinals Prediction, Picks, Odds Today: Dallas Looks To Continue Dominating Start

Is Dallas the best team in the NFL so far? Let's look at the odds, make a best bet prediction, and more for the Cowboys vs. Cardinals matchup.

The biggest road favorite in Week 3 is the Dallas Cowboys, favored by more than two touchdowns. But is that too much for a road game in the NFL? Check out the odds and the best bet for this matchup.

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Cowboys vs. Cardinals Betting Lines, Start Time, and More

All odds from DraftKings Sportsbook.

  • Spread: Cowboys -13
  • Moneyline: Cowboys (-750); Cardinals (+525)
  • Over/Under: 43
  • Game time: 4:25 p.m. ET
  • Location: State Farm Stadium
  • Channel: FOX

Game Prediction

Having completed its two-game sweep of “New York” teams in dominating fashion to start the season, Dallas gets to take on an even worse team than either the Giants or Jets.

The irony, of course, is that Arizona is dangerously close to being a 2-0 team instead of a 0-2 ballclub. The Cardinals entered the fourth quarter of their season opener with the Commanders up 16-10, before losing 20-16. And then last week they one-upped themselves, blowing a 28-7 second-half lead and losing 31-28.

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In the first two games of the season, Arizona has outscored its opponents by a combined 33-10 score but has been outscored 27-0 in the fourth quarter.

So just how can Arizona, losers of nine in a row dating back to last season, be expected to stay with a Dallas team that has outscored its first two opponents, 70-10?

First things first, it’s important to realize that as dominating as the Cowboys have been, they are averaging only 323.5 total yards per game, which ranks 18th in the NFL. And yes, Dallas leads the league in scoring at 35.0 PPG. But 14 of the Cowboys’ 70 total points are the result of defensive touchdowns in the season opener vs. the Giants.

After leading the NFL with 15 interceptions a season ago, Dak Prescott has gotten off to an impressive start this season. He has yet to throw an interception and is completing 71% of his passes.

This is the fourth time Prescott has opened a season without throwing an INT in his first two games. However, only once has he done this in the first three games to begin a season. That came as a rookie in 2016 (went his first five games without throwing a pick).

But Dallas is a running team so far. The Cowboys enter Sunday second in the NFL in rush attempts per game (37.0) and have at least 30 carries in each of their first two games.

The question in this game is can Arizona’s offense score enough to stay with the Cowboys? The Cardinals did a good job scoring last week, putting 28 points on the board against the Giants. And Arizona QB Josh Dobbs, while not a Pro Bowl-caliber quarterback, has a decent 89.5 passer rating. For perspective, Patrick Mahomes’ passer rating so far is only 88.1.

Dallas leads the NFL in takeaways (seven) and that has been a major part of its success early on. The Cardinals’ issues in Week 1 vs. the Commanders came when they turned it over twice in the second half, helping to spark the comeback by Washington.

If Arizona, which did not have a turnover last week, is sloppy again with the ball, it’ll be a long day for the Cardinals.

But it’s already looking like it will be a long day.

Give the big number and take the Cowboys.

Best Bet: Cowboys -13 points (-110 at DraftKings SportsBook)

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