Tulane vs. UTSA Prediction: Can the Roadrunners Ruin the Green Wave’s Road to the Playoff?

The Roadrunners and Green Wave collide on Thursday night, and our Tulane vs. UTSA prediction breaks down this crucial American matchup.

Under the bright lights of the Alamodome, UTSA hosts Tulane in a prime-time Thursday night showdown on ESPN, with kickoff set for 7:30 p.m. ET.

The Roadrunners (3-4, 1-2) look to protect their perfect home conference record under head coach Jeff Traylor (21-0 in regular season play). The Green Wave (6-1, 3-0) arrives aiming to spoil the streak in the teams’ third-ever meeting and second as American Conference foes.

Adding to the drama, UTSA will break out its black uniforms for the “Lights Out” game, where the program remains unbeaten at 5-0. The Tulane vs. UTSA prediction sets the stage for a pivotal clash as both teams vie for conference momentum, with potential playoff positioning at stake for the Green Wave.

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Tulane vs. UTSA Details

  • Date: Thursday, Oct. 30, 2025
  • Game time: 7:30 p.m. ET
  • Location: Alamodome | San Antonio, TX
  • Predicted Weather at Kick: 72 degrees
  • How to watch: ESPN

Tulane vs. UTSA Head-to-Head Record

Tulane and UTSA meet for just the third time Thursday night at the Alamodome, with the all-time series tied 1-1, as each team has held serve at home. The Roadrunners took the inaugural matchup in 2013 with a gritty 10-7 win, sealed by Sean Ianno’s 34-yard field goal in the final seconds after Orleans Darkwa provided Tulane’s lone touchdown.

A decade later, the Green Wave got their revenge in New Orleans when Michael Pratt connected twice with Chris Brazzell II and Makhi Hughes rumbled for 166 yards in a 29-16 victory that featured five UTSA turnovers.

This time, the stakes are high: a win in San Antonio would give Tulane 39 victories in its last 50 games, a benchmark not seen since 1935, but the Roadrunners’ fortress looms large, with Jeff Traylor’s squad unbeaten in 23 straight home conference contests.

Tulane vs. UTSA Grades

Below are the PFSN team and positional grades for the highest-ranked players set to be featured in Tulane vs. UTSA.

PFSN College OFFi

  • Tulane (75.3, C)
  • UTSA (72.2, C-)

PFSN College DEFi

  • Tulane (74, C)
  • UTSA (74.6, C)

PFSN College OLi

  • Tulane (69.6, D+)
  • UTSA (73.2, C)

PFSN College QBi

  • Jake Retzlaff, Tulane (78.2, C+)
  • Owen McCown, UTSA (73.9, C)

PFSN College RBi

  • Javin Gordon, Tulane (66.9, D)
  • Robert Henry II, UTSA (78.8, C+)

PFSN College WRi

  • Omari Hayes, Tulane (81.2, B-)
  • AJ Wilson, UTSA (79.9, C+)

PFSN College TEi 

  • Johnny Pascuzzi, Tulane (72.4, C-)
  • Houston Thomas, UTSA (74.9, C)

PFSN College EDGEi

  • Harvey Dyson, Tulane (70.8, C-)
  • Nnanna Anyanwu, UTSA (70.5, C-)

PFSN College DTi

  • Santana Hopper, Tulane (83.1, B)
  • Kenny Ozowalu (77.7, C+)

PFSN College LBi

  • Chris Rodgers, Tulane (63.8, D)
  • Shad Banks Jr., UTSA (68.4, D+)

PFSN College CBi

  • KC Eziomume, Tulane (63.4, D)
  • Davin Martin, UTSA (79.7, C+)

PFSN College SAFi

  • Javion White, Tulane (81.4, B-)
  • Jimmy Wyrick, UTSA (80.6, B-)

Tulane vs. UTSA Prediction

Tulane appears well-positioned to keep its College Football Playoff hopes alive as it heads to San Antonio. While UTSA has enjoyed home-field strength under Traylor, this year’s Roadrunners have shown inconsistency, ranging from a 61-13 victory over Rice to a 55-17 defeat against North Texas.

In contrast, Tulane’s only loss came against Ole Miss, and Jon Sumrall’s team has demonstrated resilience with wins over Northwestern and Duke. The Green Wave’s balanced attack, averaging 6.65 yards per play in conference play and allowing just 4.7 yards per play defensively, gives them a clear advantage over a UTSA squad still seeking offensive consistency.

Prediction: Tulane, 28 UTSA, 21

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