Tulane vs. Ole Miss Prediction: Can the Green Wave Gain Revenge in the College Football Playoff?

No. 6 Ole Miss hosts No. 11 Tulane in the first round of the College Football Playoff as both teams look to advance to the CFP quarterfinals.

No. 6 Ole Miss will host No. 11 Tulane in the first round of the 2026 College Football Playoff, with both teams aiming to extend their postseason runs and advance to the CFP quarterfinals. Ole Miss finished the season 11-1 (7-1 SEC), while Tulane ended 11-2 (7-1 AAC) and won the AAC championship, earning a spot in the playoff.

This matchup marks a rematch from earlier this season. On Sept. 20, 2025, Ole Miss defeated Tulane 45-10 in Oxford. While Tulane enters with hopes of a different outcome, Ole Miss looks to repeat its dominant performance on its home field.

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Tulane vs. Ole Miss Details

  • Date: Saturday, Dec. 20, 2025
  • Game time: 3:30 p.m. ET
  • Location: Vaught Hemingway Stadium in Oxford, Mississippi
  • Predicted weather at kick: 60 degrees
  • How to watch: TNT, truTV, HBO Max

Tulane vs. Ole Miss Head-to-Head Record

Saturday’s playoff game will be the 68th meeting between Ole Miss and Tulane. The series began on Dec. 2, 1893, when Ole Miss earned a 12-4 victory. Since then, the Rebels have maintained a strong edge, holding a 41-27 record over the Green Wave.

Ole Miss has controlled the recent history of the series, riding a 14-game winning streak against Tulane dating back to their matchup on Oct. 21, 1989. The Rebels look to extend that streak in their first-ever CFP matchup against the Green Wave.

Tulane vs. Ole Miss Grades

PFSN College OFFi

  • Tulane (76.8, C)
  • Ole Miss (85.3, B)

PFSN College DEFi

  • Tulane (73.9, C)
  • Ole Miss (82.4, B-)

PFSN College OLi

  • Tulane (72.7, C-)
  • Ole Miss (84.4, B)

PFSN College QBi

  • Jake Retzlaff, Tulane (86.6, B)
  • Trinidad Chambliss, Ole Miss (90.3, A-)

PFSN College RBi

  • Jamauri McClure, Tulane (72.7, C-)
  • Kewan Lacy, Ole Miss (90.2, A-)

PFSN College WRi

  • Omari Hayes, Tulane (79.8, C+)
  • Harrison Wallace III, Ole Miss (78.9, C+)

PFSN College TEi

  • Johnny Pascuzzi, Tulane (73.5, C)
  • Dae’Quan Wright, Ole Miss (80.6, B-)

PFSN College EDGEi

  • Harvey Dyson, Tulane (69, D+)
  • Princewill Umanmielen, Ole Miss (77.9, C+)

PFSN College DTi

  • Santana Hopper, Tulane (85.7, B)
  • Will Echoles, Ole Miss (82.7, B-)

PFSN College LBi

  • Chris Rodgers, Tulane (73.5, C)
  • TJ Dottery, Ole Miss (74.4, C)

PFSN College CBi

  • Jahiem Johnson, Tulane (82.3, B-)
  • Antonio Kite, Ole Miss (77.8, C+)

PFSN College SAFi

  • Javion White, Tulane (80.2, B-)
  • Wydett Williams Jr., Ole Miss (92.5, A-)

Tulane vs. Ole Miss Prediction

Ole Miss enters the CFP with a higher seed and home-field advantage, but the Rebels will do so under new leadership. Former head coach Lane Kiffin departed for LSU following the regular season, leading Ole Miss to hire defensive coordinator Pete Golding as head coach. Golding’s familiarity with the roster and extensive defensive background should help the team maintain momentum as it transitions into postseason play.

MORE: Pete Golding Sets the Standard for Ole Miss Football Future as Rebels Prepare for Tulane Rematch

For the Rebels, quarterback Trinidad Chambliss remains a key factor. Chambliss has thrown for 3,016 yards and 18 touchdowns, adding six rushing scores, showcasing his ability to lead the offense. He is supported by wide receiver Harrison Wallace III and running back Kewan Lacy, giving Ole Miss a balanced attack.
Tulane counters with dual-threat quarterback Jake Retzlaff. Retzlaff has thrown for 2,862 yards and 16 touchdowns while also leading the team in rushing with 610 yards and 16 scores. His versatility has been central to Tulane’s success, but Ole Miss limited his impact earlier this season, holding him without a touchdown.
With Golding’s defensive expertise and a playoff-tested roster, Ole Miss appears well-positioned to contain Tulane’s offense once again. While the Green Wave has earned its place in the CFP, the Rebels’ experience and home-field advantage give them the edge in this first-round matchup.

Prediction: Tulane 17, Ole Miss 38

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