Titans vs. Colts prediction, pick, odds, and how to watch the Week 8 game

The Jaguars (1-5) and Texans (1-6) are in a race for the No. 1 overall pick in the 2022 NFL Draft. Thus, only the Colts (3-2) have a chance of taking the division crown from the Titans (5-2). Tennessee already picked up a 25-16 win over Indianapolis earlier in the year. Can they go 2-0 against their AFC South rival this season? Here is a Titans vs. Colts prediction, along with the NFL odds, TV channel, live stream options, and how to listen to this divisional matchup.

Tennessee Titans vs. Indianapolis Colts prediction and odds | Week 8

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• Spread: Titans -1
• Moneyline: Titans -120, Colts +100
• Over/Under: 48.5

Odds from DraftKings sportsbook

One of the hottest teams in the NFL currently, the Titans are fresh off upsets against the Bills and Chiefs. Although Kansas City is not the world-beater we imagined entering the season, Tennessee made them look utterly pedestrian in a 27-3 victory last week.

The Colts have scored 25+ points in four straight games, going 3-1 in that span (the one loss coming in overtime to the Ravens). Both offenses are catching their stride, with health playing a key role over the past few weeks. Julio Jones and A.J. Brown are finally on the field together in Tennessee, and T.Y. Hilton and Braden Smith should be good to go for Indy in Week 8.

The Colts hold a 35-19 series lead over the Titans, but these are different times. Derrick Henry is pillaging every defense across from him and is rushing straight toward NFL record books. When they’re both at 100%, Jones and Brown offer Ryan Tannehill possibly the best one-two wide receiver punch in the league. Can the Colts keep up?

Titans vs. Colts prediction

Henry is going to get his, while Brown has the skill set to make defenders look silly in the open field. If Jones can return to his usual dominant self and Tannehill can put it on him, the Titans should pick up a win on the road.

Each team’s secondary is banged up and struggling to defend the pass. With the Colts having their own standout RB in Jonathan Taylor, this game likely comes down to the aerial assaults. So, who do you trust more: Carson Wentz, Michael Pittman Jr., and Hilton, or Tannehill, Brown, and Jones?

Adding to the betting allure, both squads are 5-2 against the spread and own a similar 4-3 over-under record. Divisional games tend to be trickier to predict, but I anticipate the Titans covering, winning straight up, and hitting the over.

Prediction: Titans 28, Colts 24

How to watch and listen to Titans vs. Colts this week

• Start time: 1 PM ET
• Channel: CBS
• Live stream:
  • Sling
  • fuboTV
  • Youtube TV
  • Hulu + Live TV
  • NFL Mobile App
  • NFL Sunday Ticket
  • Paramount+
• Listen:
  • TuneIn Radio
  • Sirius XM Radio
  • Local Indianapolis: The Fan 93.5/107.5 FM, HANK 97.1 FM
  • Local Tennessee: The Zone 104.5 FM