Seahawks vs. 49ers prediction, odds, line, and how to watch the Week 4 game

What are the Seahawks vs. 49ers odds and prediction, what channel is the game on, and how can you stream this Week 4 matchup?

Sunday’s Seattle Seahawks vs. San Francisco 49ers game features two teams looking to keep pace in an ultra-competitive NFC West. Let’s look at the current lines and NFL odds, a prediction for the game, the TV channel, and where and how to live stream the Seahawks vs. 49ers Week 4 NFL game.

Seattle Seahawks vs. San Francisco 49ers prediction and odds | Week 4

Odds provided by DraftKings sportsbook.

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  • Spread: 49ers -3
  • Moneyline: Seahawks +130, 49ers -150
  • Over/Under: 52.5 (Over -110, Under -110)

The Seahawks’ season might only be 12 quarters through, but it’s already been a season of two halves. Through halftime of their Week 2 game against Tennessee, Seattle led 24-9 and was on course for a 2-0 start. That’s when things changed. Through the second half and overtime, the Titans outscored them 24-6 and won 33-30.

They looked like they had stopped the skid in Week 3 when they led the Vikings 17-7 early in the second quarter. However, from that point, the Vikings scored 23 unanswered points to win comfortably by 13 (30-17). Suddenly, the Seahawks are looking down the barrel at being three games out of first place if they lose in Week 3.

Meanwhile, the 49ers were one play away from a 3-0 start. Instead, they are 2-1 and facing the potential of being two games out of first place in the NFC West if they lose this week. That is what makes predictions for this Seahawks vs. 49ers game so hard to make, as both sides already have so much on the line going into Week 4.

Seahawks vs. 49ers prediction

The Seahawks have a good history against the 49ers. Dating back to the NFC Championship Game in 2014, the Seahawks are 13-2 against the 49ers. However, over the past five meetings, the games between these two have generally been tight. Only last year’s Week 8 game between these two was decided by more than a touchdown.

Additionally, the 49ers do not look like a team playing smoothly right now. Hampered by injuries, the offense has struggled at times in the last two weeks. In fact, the 49ers had to turn to Trey Lance a couple of times near the goal line in Week 3 to provide a spark.

Playing against an explosive offense like the Seahawks will test the 49ers’ defense. Nevertheless, their defensive line should be able to get the better of the Seahawks’ concerning offensive line in this one.

Prediction: 49ers 24, Seahawks 21

How to watch and listen to Seahawks vs. 49ers this week

  • Start: 4:05 PM ET
  • Channel: FOX
  • Listen: Seahawks | KIRO 710 AM ESPN; 49ers | KSAN 107.7 FM (“The Bone”) & KTCT 1050 AM
  • Live Streaming Options:
    • Sling
    • Hulu + Live TV
    • fuboTV
    • YouTube TV
    • DirecTV NFL Sunday Ticket
    • NFL Mobile App

Ben Rolfe is a Senior Managing Editor at Pro Football Network and is also a member of the Fantasy Sports Writers Association (FSWA). You can find him on Twitter @BenRolfePFN