If you’re planning to make Week 2 NFL prop bets for Monday Night Football’s Philadelphia Eagles vs. Minnesota Vikings or Buffalo Bills vs. Tennessee Titans matchups, then you’ve come to the right place. We’ve analyzed the game’s highest-probability scripts to assess the most likely outcomes, including which players are in line to thrive more than anticipated as well as fall short of expectations. All prop bets are based on FanDuel Sportsbook or BetMGM.
Top prop bets to target
The following NFL betting recommendations are based on proprietary PFN predictive analytics culled from decades of NFL historical data. Using this data, I’ve built dozens of models showing actionable probabilities of better-than-expected and worse-than-expected outcomes. Criteria such as age, durability, shifting personnel, scheduling, and other factors help shape these final assessments.
Eagles Week 2 prop bets
How good is DeVonta Smith? The only reason he’s not the Eagles’ unquestioned No. 1 receiver is that they traded for one of the best in the game. Sure, Smith underwhelmed last year more often than not. But the 2021 first-rounder remains one of the best receiving prospects in the game. If Philly wants to go deep into the playoffs, they’ll need more than A.J. Brown anchoring their passing attack. They’ll need to well-developed No. 2. Expect Smith to get more attention tonight.
As for Miles Sanders, I’m not as confident. His performance last weekend was a statement game after an inexplicably scoreless 2021 campaign. With Kenneth Gainwell and Boston Scott backing him up (and really, Gainwell is more of a glorified handcuff), Sanders easily could get phased out of this one, particularly if the Eagles are behind in the second half. Sanders’ path to exceeding expectations is relatively narrow.
Smith scores the first TD (+1400) — FanDuel
Smith scores the last TD (+1400) — FanDuel
Smith receptions over 3.5 (+124) — FanDuel
Smith receiving yards over 42.5 (-113) — FanDuel
Sanders rushing yards over 57.5 (-115) — BetMGM
Vikings Week 2 prop bets
As today’s kids like to say, “Justin Jefferson knows how to run, catch, and run some more.” He was my preseason WR1 (ahead of Cooper Kupp) based on the simple belief that we don’t yet know how good he can be. Last week we caught a glimpse. This week he should remain a focal point of Minnesota’s offense.
But not so fast! Jefferson can’t do it all alone through the air. And with Irv Smith still getting his sea legs, and with K.J. Osborn seemingly locked into a semi-permanent No. 3 WR role, we’re left with the aging-but-still-talented Adam Thielen. I like him posting better numbers tonight than we saw last week when he posted a barely audible 3-36-0 receiving line. Vikings fans demand more, and Thielen should get more.
Jefferson receptions over 7.5 (+124) — FanDuel
Jefferson receiving yards over 98.5 (-113) — FanDuel
Thielen scores the first TD (+1100) — FanDuel
Thielen scores the last TD (+1000) — FanDuel
Thielen receptions over 4.5 (+108) — FanDuel
Bills Week 2 prop bets
I don’t think Josh Allen will need to do too much through the air tonight. Maybe next week. But at home against the potentially struggling Titans, Allen might not crack 225 yards. Instead, Buffalo should be able to win with their defense, some timely passing, and a lot of RB work. With a short week upcoming before traveling to Miami, the Bills might put this game in cruise control by late in the third quarter.
As a result, I think we’ll see a decent amount of Devin Singletary, the de facto leader of Buffalo’s backfield. James Cook lost a fumble in his debut, and Zack Moss remains comfortably behind on the depth chart. Singletary should see enough touches to generate 65+ total yards and a score.
Allen passing yards under 261.5 (-115) — BetMGM
Allen rushing yards under 40.5 (-115) — BetMGM
Singletary scores the first TD (+800) — BetMGM
Singletary rushing yards over 44.5 (-115) — FanDuel
Titans Week 2 prop bets
Finally, the Titans. One of the league’s toughest schedules and least proven receiving corps. Ah, but they have one of the best running backs . . . who might not be one of the best anymore. Can Derrick Henry carry this franchise like he did for much of the first half of last season?
And what about Robert Woods? Entering 2022, he was one of only five WRs who had averaged 15+ PPR fantasy points per game in each of the last four seasons. This year he might be lucky to average eight. Sure, it’s still early. There are 16 games remaining. And yet, when we examine Tennessee’s brutal schedule and Woods’ questionable weekly role, there are reasons to be concerned.
Henry rushing attempts under 21.5 (-114) — FanDuel
Henry rushing yards under 88.5 (-115) — BetMGM
Woods receiving yards under 41.5 (-113) — FanDuel
