Matthew Stafford Fantasy Hub: Week 5 Injury Update, Start ‘Em/Sit ‘Em Advice, Points Projection, and Weather Impact

Here's this week's fantasy football outlook for Matthew Stafford, including injury updates, start-sit advice, points projection, and weather impact.

The Los Angeles Rams (3-1) will host the San Francisco 49ers (3-1) in Week 5. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, specifically regarding QB Matthew Stafford.

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Is Matthew Stafford Playing in Week 5?

Stafford is not on the injury report and is expected to play.

We’ll continue to monitor the Rams’ injury report leading up to kickoff for any changes. You can also visit and bookmark our Fantasy News Tracker for the latest updates.

Should You Start or Sit Matthew Stafford in Week 5?

Matthew Stafford piled up the numbers over the weekend against the previously unbeaten Colts (375 pass yards and three touchdowns) on his way to a QB2 finish.

That’s great, but I can’t imagine that you’re overreacting to that performance and considering him in single-QB leagues.

Despite Puka Nacua being on a historic pace and the honing in on Davante Adams during red-zone situations, this was Stafford’s first weekly finish inside the top 15 at the position.

He ran hot on Sunday, but in looking at September as a whole, where is Stafford supposed to improve?

The Rams have failed to clear 23 real-life points in five of six games against the 49ers since 2022 (17.7 PPG), and Stafford hasn’t scored 20 fantasy points against San Francisco since joining Los Angeles (12.4 PPG).

Last week was fun, but I’d keep that in the past and not project it to continue.

Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.

Stafford’s Fantasy Points Projection in Week 5

Stafford is projected to score 14.6 fantasy points in PPR formats.

We project Stafford to throw for 229 yards and 1.4 passing touchdowns with 0.7 interceptions. Stafford could also add 2 rushing yards on the ground.

Check out the free PFSN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.

Week 5 Weather Impact: 49ers at Rams

Since the Rams play in a dome, there is no weather impact for this Week 5 matchup. Temperatures will be a comfortable 72 degrees Fahrenheit with no wind.

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