Matthew Stafford Fantasy Hub: Week 10 Injury Update, Start ‘Em/Sit ‘Em Advice, Points Projection, and Weather Impact

Here's this week's fantasy football outlook for Matthew Stafford, including injury updates, start-sit advice, points projection, and weather impact.

The Los Angeles Rams will visit the San Francisco 49ers in Week 10. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, specifically regarding QB Matthew Stafford.

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Is Stafford Playing in Week 10?

Stafford is not on the injury report and barring a surprise, he is expected to play.

We’ll continue to monitor the Rams’ injury report leading up to kickoff for any changes. You can also visit and bookmark our Fantasy News Tracker for the latest updates.

Should You Start or Sit Stafford in Week 10?

It’s difficult to survive in this fantasy world of ours with next to zero rushing equity, but Matthew Stafford’s current form is about what it takes.

He’s thrown nine touchdown passes over his past two games and has at least two through the air in six of his past seven games. The highlight from last week being an absolute dime to Puka Nacua to beat nearly perfect coverage as part of a 15-for-18 start (164 yards and three scores).

Stafford is pacing toward his best YPA season since 2021 and wasn’t shy about featuring his favorites in the Week 5 meeting against these Niners (71.7% of his targets went to Nacua, Davante Adams, or Kyren Williams).

Due to some of the dual-threat QBs having favorable matchups, I can’t get Stafford inside of my top 10 this week, but he’s not far from it and is trending as strong as any pocket passer in the sport.

Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.

Stafford’s Fantasy Points Projection in Week 10

Stafford is projected to score 17.0 fantasy points in PPR formats.

We project Stafford to throw for 268 yards and 1.7 passing touchdowns with 0.8 interceptions. Stafford could also add 3 rushing yards on the ground.

Check out the free PFSN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.

Week 10 Weather Impact: Rams at 49ers

The forecast for kickoff is 77 degrees Fahrenheit with 2 mph winds. These are ideal conditions for fantasy production.

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