Week 4 Fantasy WR Rankings: Start-Sit Advice for Puka Nacua, Brian Thomas Jr., Nico Collins, and Others

Week 4 of the fantasy football season has arrived, and it’s more important than ever to know which players deserve a place in your starting lineup. Considering player talent, recent form, and matchups, we’ve put together our PFSN consensus Week 4 WR rankings.

These rankings were last updated at 9:00 AM ET on Sunday, September 28, 2025.

Week 4 WR Fantasy Rankings

1) Puka Nacua | Los Angeles Rams (vs. IND)
2) Malik Nabers | New York Giants (vs. LAC)
3) Jaxon Smith-Njigba | Seattle Seahawks (at ARI)
4) Amon-Ra St. Brown | Detroit Lions (vs. CLE)
5) Justin Jefferson | Minnesota Vikings (vs. PIT (Ireland))
6) Ja’Marr Chase | Cincinnati Bengals (at DEN)
7) Nico Collins | Houston Texans (vs. TEN)
8) Drake London | Atlanta Falcons (vs. WAS)
9) Zay Flowers | Baltimore Ravens (at KC)
10) Rome Odunze | Chicago Bears (at LV)
11) Garrett Wilson | New York Jets (at MIA)
12) Davante Adams | Los Angeles Rams (vs. IND)
13) A.J. Brown | Philadelphia Eagles (at TB)
14) Emeka Egbuka | Tampa Bay Buccaneers (vs. PHI)
15) Courtland Sutton | Denver Broncos (vs. CIN)
16) Tetairoa McMillan | Carolina Panthers (at NE)
17) Ladd McConkey | Los Angeles Chargers (at NYG)
18) Deebo Samuel Sr. | Washington Commanders (at ATL)
19) George Pickens | Dallas Cowboys (vs. GB)
20) Ricky Pearsall | San Francisco 49ers (vs. JAX)
21) Tyreek Hill | Miami Dolphins (vs. NYJ)
22) Keenan Allen | Los Angeles Chargers (at NYG)
23) DeVonta Smith | Philadelphia Eagles (at TB)
24) Jakobi Meyers | Las Vegas Raiders (vs. CHI)
25) Quentin Johnston | Los Angeles Chargers (at NYG)
26) DK Metcalf | Pittsburgh Steelers (vs. MIN (Ireland))
27) Chris Olave | New Orleans Saints (at BUF)
28) DJ Moore | Chicago Bears (at LV)
29) Brian Thomas Jr. | Jacksonville Jaguars (at SF)
30) Marvin Harrison Jr. | Arizona Cardinals (vs. SEA)
31) Jameson Williams | Detroit Lions (vs. CLE)
32) Tee Higgins | Cincinnati Bengals (at DEN)
33) Michael Pittman Jr. | Indianapolis Colts (at LAR)
34) Jauan Jennings | San Francisco 49ers (vs. JAX)
35) Xavier Worthy | Kansas City Chiefs (vs. BAL)
36) Jaylen Waddle | Miami Dolphins (vs. NYJ)
37) Jordan Addison | Minnesota Vikings (vs. PIT (Ireland))
38) Khalil Shakir | Buffalo Bills (vs. NO)
39) Darnell Mooney | Atlanta Falcons (vs. WAS)
40) Wan’Dale Robinson | New York Giants (vs. LAC)
41) Calvin Ridley | Tennessee Titans (at HOU)
42) Romeo Doubs | Green Bay Packers (at DAL)
43) Jerry Jeudy | Cleveland Browns (at DET)
44) Cedric Tillman | Cleveland Browns (at DET)
45) Rashid Shaheed | New Orleans Saints (at BUF)
46) Elic Ayomanor | Tennessee Titans (at HOU)
47) Cooper Kupp | Seattle Seahawks (at ARI)
48) Parker Washington | Jacksonville Jaguars (at SF)
49) Travis Hunter | Jacksonville Jaguars (at SF)
50) Hollywood Brown | Kansas City Chiefs (vs. BAL)

Emeka Egbuka, Tampa Bay Buccaneers

The stars continue to align for Emeka Egbuka’s rise to fantasy stardom. Before week three, we got a report that Chris Godwin Jr. has “a strong chance” to return in Week 4. The concern with Egbuka was always his role with Godwin and Mike Evans, who are both healthy and active. We do not have to worry about that for at least one more week.

Just as Godwin is set to make his season debut, Evans will now miss a little time with what is described as a mild hamstring strain. That means Egbuka is set to serve as Baker Mayfield’s primary target for the first time in this week’s showdown with the Philadelphia Eagles.

The Eagles have been an average defense against wide receivers, allowing the 14th most fantasy points per game to the position. However, last week, we saw what can happen when they face a very formidable wide receiver duo. Puka Nacua and Davante Adams combined to catch 14 passes for 168 yards and a touchdown.

Egbuka is coming off his best game yet, hauling in six balls for 85 yards, including some clutch receptions late in the fourth quarter. His trust and rapport with Mayfield is only growing.

Even if Godwin does return, he will not be able to play a full complement of snaps. The rookie will be the WR1 for this week’s game, which could be high-scoring. Egbuka is a borderline WR1.

Brian Thomas Jr., Jacksonville Jaguars

I wish I had an answer for you, I really do.

The 46-yard catch late helped Brian Thomas save himself from the worst game of his season, but another game with a sub-35% catch rate and no real scoring chances through the pass game isn’t exactly what the fantasy doctor ordered.

The rushing touchdown in Week 1 has accounted for 27.2% of his fantasy points this season, an absolutely bizarre note for a player that looked like the next big thing after his standout rookie campaign.

We are long done with Stefon Diggs and DeAndre Hopkins as lineup locks, or even rosterable players in most situations, but they both have top-40 weekly finishes this season, a claim that BTJ cannot make.

Whether this is a Trevor Lawrence thing, a Liam Coen thing, a Thomas thing, or some combination of the three, this is clearly a broken situation that needs to prove itself to us before we keep burning a starting lineup spot on it.

I would have never thought that Quentin Johnston over Thomas in Week 4 would be an easy call or that an underwhelming Matthew Golden over Thomas would be a serious question at this point, but that’s where we are.

I have Thomas ranked as WR37, and I’d be thrilled to be wrong. But at this point, I’ll be late to the come-up instead of being in front of it.