Fantasy Football FLEX Rankings: Updated Week 16 Start-Sit for Emeka Egbuka, Shedeur Sanders, Nick Chubb, and Others

Take a look at our Week 16 consensus FLEX rankings to help with your lineup choices, including start-sit recommendations, waiver wire targets, and more.

Week 16 of the fantasy football season has arrived, and it’s more important than ever to know which players deserve a place in your starting lineup. Considering player talent, recent form, and matchups, we’ve put together our PFSN consensus Week 16 FLEX rankings.

These rankings were last updated at 7:00 AM ET on Sunday, December 21, 2025.

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Week 16 Top Fantasy FLEX Rankings

1) Puka Nacua, WR | Los Angeles Rams (at SEA)
2) Ja’Marr Chase, WR | Cincinnati Bengals (at MIA)
3) Christian McCaffrey, RB | San Francisco 49ers (at IND)
4) Jahmyr Gibbs, RB | Detroit Lions (vs. PIT)
5) Bijan Robinson, RB | Atlanta Falcons (at ARI)
6) Jaxon Smith-Njigba, WR | Seattle Seahawks (vs. LAR)
7) Amon-Ra St. Brown, WR | Detroit Lions (vs. PIT)
8) De’Von Achane, RB | Miami Dolphins (vs. CIN)
9) Nico Collins, WR | Houston Texans (vs. LV)
10) CeeDee Lamb, WR | Dallas Cowboys (vs. LAC)
11) Drake London, WR | Atlanta Falcons (at ARI)
12) James Cook, RB | Buffalo Bills (at CLE)
13) Mike Evans, WR | Tampa Bay Buccaneers (at CAR)
14) Jaylen Waddle, WR | Miami Dolphins (vs. CIN)
15) Trey McBride, TE | Arizona Cardinals (vs. ATL)
16) Josh Jacobs, RB | Green Bay Packers (at CHI)
17) A.J. Brown, WR | Philadelphia Eagles (at WAS)
18) Saquon Barkley, RB | Philadelphia Eagles (at WAS)
19) Jonathan Taylor, RB | Indianapolis Colts (vs. SF)
20) Chase Brown, RB | Cincinnati Bengals (at MIA)
21) Jameson Williams, WR | Detroit Lions (vs. PIT)
22) Woody Marks, RB | Houston Texans (vs. LV)
23) Michael Wilson, WR | Arizona Cardinals (vs. ATL)
24) George Kittle, TE | San Francisco 49ers (at IND)
25) Travis Etienne Jr., RB | Jacksonville Jaguars (at DEN)
26) Christian Watson, WR | Green Bay Packers (at CHI)
27) Tetairoa McMillan, WR | Carolina Panthers (vs. TB)
28) DK Metcalf, WR | Pittsburgh Steelers (at DET)
29) Chris Olave, WR | New Orleans Saints (vs. NYJ)
30) TreVeyon Henderson, RB | New England Patriots (at BAL)
31) Bucky Irving, RB | Tampa Bay Buccaneers (at CAR)
32) Jauan Jennings, WR | San Francisco 49ers (at IND)
33) Javonte Williams, RB | Dallas Cowboys (vs. LAC)
34) RJ Harvey, RB | Denver Broncos (vs. JAX)
35) Derrick Henry, RB | Baltimore Ravens (vs. NE)
36) Kyle Pitts Sr., TE | Atlanta Falcons (at ARI)
37) D’Andre Swift, RB | Chicago Bears (vs. GB)
38) Kyren Williams, RB | Los Angeles Rams (at SEA)
39) Tee Higgins, WR | Cincinnati Bengals (at MIA)
40) Aaron Jones Sr., RB | Minnesota Vikings (at NYG)
41) Quinshon Judkins, RB | Cleveland Browns (vs. BUF)
42) Terry McLaurin, WR | Washington Commanders (vs. PHI)
43) Zay Flowers, WR | Baltimore Ravens (vs. NE)
44) Ladd McConkey, WR | Los Angeles Chargers (at DAL)
45) Brock Bowers, TE | Las Vegas Raiders (at HOU)
46) Breece Hall, RB | New York Jets (at NO)
47) Jakobi Meyers, WR | Jacksonville Jaguars (at DEN)
48) Courtland Sutton, WR | Denver Broncos (vs. JAX)
49) Marvin Harrison Jr., WR | Arizona Cardinals (vs. ATL)
50) Chris Godwin, WR | Tampa Bay Buccaneers (at CAR)
51) Wan’Dale Robinson, WR | New York Giants (vs. MIN)
52) Brian Thomas Jr., WR | Jacksonville Jaguars (at DEN)
53) DJ Moore, WR | Chicago Bears (vs. GB)
54) Tyrone Tracy Jr., RB | New York Giants (vs. MIN)
55) Omarion Hampton, RB | Los Angeles Chargers (at DAL)
56) Travis Kelce, TE | Kansas City Chiefs (at TEN)
57) Colby Parkinson, TE | Los Angeles Rams (at SEA)
58) Rico Dowdle, RB | Carolina Panthers (vs. TB)
59) George Pickens, WR | Dallas Cowboys (vs. LAC)
60) Jaylen Warren, RB | Pittsburgh Steelers (at DET)
61) Tony Pollard, RB | Tennessee Titans (vs. KC)
62) Michael Carter, RB | Arizona Cardinals (vs. ATL)
63) DeVonta Smith, WR | Philadelphia Eagles (at WAS)
64) Michael Pittman Jr., WR | Indianapolis Colts (vs. SF)
65) Stefon Diggs, WR | New England Patriots (at BAL)
66) Deebo Samuel Sr., WR | Washington Commanders (vs. PHI)
67) Rhamondre Stevenson, RB | New England Patriots (at BAL)
68) Kenneth Gainwell, RB | Pittsburgh Steelers (at DET)
69) Emeka Egbuka, WR | Tampa Bay Buccaneers (at CAR)
70) Dallas Goedert, TE | Philadelphia Eagles (at WAS)
71) Ashton Jeanty, RB | Las Vegas Raiders (at HOU)
72) Quentin Johnston, WR | Los Angeles Chargers (at DAL)
73) Zach Charbonnet, RB | Seattle Seahawks (vs. LAR)
74) Kenneth Walker III, RB | Seattle Seahawks (vs. LAR)
75) Kimani Vidal, RB | Los Angeles Chargers (at DAL)
76) David Montgomery, RB | Detroit Lions (vs. PIT)
77) Jordan Addison, WR | Minnesota Vikings (at NYG)
78) Tyler Warren, TE | Indianapolis Colts (vs. SF)
79) Harold Fannin Jr., TE | Cleveland Browns (vs. BUF)
80) Jayden Reed, WR | Green Bay Packers (at CHI)
81) Chuba Hubbard, RB | Carolina Panthers (vs. TB)
82) Kyle Monangai, RB | Chicago Bears (vs. GB)
83) Kareem Hunt, RB | Kansas City Chiefs (at TEN)
84) Khalil Shakir, WR | Buffalo Bills (at CLE)
85) Dalton Schultz, TE | Houston Texans (vs. LV)
86) Adonai Mitchell, WR | New York Jets (at NO)
87) Blake Corum, RB | Los Angeles Rams (at SEA)
88) Keenan Allen, WR | Los Angeles Chargers (at DAL)
89) Xavier Worthy, WR | Kansas City Chiefs (at TEN)
90) Jayden Higgins, WR | Houston Texans (vs. LV)
91) Jerry Jeudy, WR | Cleveland Browns (vs. BUF)
92) Devin Singletary, RB | New York Giants (vs. MIN)
93) Alec Pierce, WR | Indianapolis Colts (vs. SF)
94) Jalen Coker, WR | Carolina Panthers (vs. TB)
95) Kayshon Boutte, WR | New England Patriots (at BAL)
96) Tyjae Spears, RB | Tennessee Titans (vs. KC)
97) Jordan Mason, RB | Minnesota Vikings (at NYG)
98) Darius Slayton, WR | New York Giants (vs. MIN)
99) Dalton Kincaid, TE | Buffalo Bills (at CLE)
100) Justin Jefferson, WR | Minnesota Vikings (at NYG)
101) Audric Estimé, RB | New Orleans Saints (vs. NYJ)
102) Evan Hull, RB | New Orleans Saints (vs. NYJ)
103) Colston Loveland, TE | Chicago Bears (vs. GB)
104) Chris Rodriguez Jr., RB | Washington Commanders (vs. PHI)
105) Chimere Dike, WR | Tennessee Titans (vs. KC)
106) Rashid Shaheed, WR | Seattle Seahawks (vs. LAR)
107) Olamide Zaccheaus, WR | Chicago Bears (vs. GB)
108) Tyler Allgeier, RB | Atlanta Falcons (at ARI)
109) Rachaad White, RB | Tampa Bay Buccaneers (at CAR)
110) T.J. Hockenson, TE | Minnesota Vikings (at NYG)
111) Samaje Perine, RB | Cincinnati Bengals (at MIA)
112) Romeo Doubs, WR | Green Bay Packers (at CHI)
113) John Metchie III, WR | New York Jets (at NO)
114) Isiah Pacheco, RB | Kansas City Chiefs (at TEN)
115) Brian Robinson Jr., RB | San Francisco 49ers (at IND)
116) Theo Johnson, TE | New York Giants (vs. MIN)
117) Josh Downs, WR | Indianapolis Colts (vs. SF)
118) Tre Tucker, WR | Las Vegas Raiders (at HOU)
119) Andrei Iosivas, WR | Cincinnati Bengals (at MIA)
120) Hollywood Brown, WR | Kansas City Chiefs (at TEN)
121) Elic Ayomanor, WR | Tennessee Titans (vs. KC)
122) Oronde Gadsden II, TE | Los Angeles Chargers (at DAL)
123) Cooper Kupp, WR | Seattle Seahawks (vs. LAR)
124) Jeremy McNichols, RB | Washington Commanders (vs. PHI)
125) Xavier Legette, WR | Carolina Panthers (vs. TB)
126) Darren Waller, TE | Miami Dolphins (vs. CIN)
127) Pat Bryant, WR | Denver Broncos (vs. JAX)
128) Troy Franklin, WR | Denver Broncos (vs. JAX)
129) Jaylen Wright, RB | Miami Dolphins (vs. CIN)
130) Malik Washington, WR | Miami Dolphins (vs. CIN)
131) Ty Johnson, RB | Buffalo Bills (at CLE)
132) Mack Hollins, WR | New England Patriots (at BAL)
133) Hunter Henry, TE | New England Patriots (at BAL)
134) Emanuel Wilson, RB | Green Bay Packers (at CHI)
135) Sean Tucker, RB | Tampa Bay Buccaneers (at CAR)
136) Brenton Strange, TE | Jacksonville Jaguars (at DEN)
137) Ryan Flournoy, WR | Dallas Cowboys (vs. LAC)
138) Ollie Gordon II, RB | Miami Dolphins (vs. CIN)
139) Juwan Johnson, TE | New Orleans Saints (vs. NYJ)
140) Jawhar Jordan, RB | Houston Texans (vs. LV)
141) Parker Washington, WR | Jacksonville Jaguars (at DEN)
142) Christian Kirk, WR | Houston Texans (vs. LV)
143) Nick Chubb, RB | Houston Texans (vs. LV)
144) Kevin Austin Jr., WR | New Orleans Saints (vs. NYJ)
145) Mark Andrews, TE | Baltimore Ravens (vs. NE)
146) Jaleel McLaughlin, RB | Denver Broncos (vs. JAX)
147) Isaac TeSlaa, WR | Detroit Lions (vs. PIT)
148) Ameer Abdullah, RB | Indianapolis Colts (vs. SF)
149) Emari Demercado, RB | Arizona Cardinals (vs. ATL)
150) Marvin Mims Jr., WR | Denver Broncos (vs. JAX)
151) Mike Gesicki, TE | Cincinnati Bengals (at MIA)
152) AJ Barner, TE | Seattle Seahawks (vs. LAR)
153) Jake Ferguson, TE | Dallas Cowboys (vs. LAC)
154) Dawson Knox, TE | Buffalo Bills (at CLE)
155) Jack Bech, WR | Las Vegas Raiders (at HOU)
156) Jacory Croskey-Merritt, RB | Washington Commanders (vs. PHI)
157) Isaiah Hodgins, WR | New York Giants (vs. MIN)
158) Darnell Mooney, WR | Atlanta Falcons (at ARI)
159) Malik Davis, RB | Dallas Cowboys (vs. LAC)
160) Calvin Austin III, WR | Pittsburgh Steelers (at DET)
161) Isaiah Davis, RB | New York Jets (at NO)
162) DeAndre Hopkins, WR | Baltimore Ravens (vs. NE)
163) Rasheen Ali, RB | Baltimore Ravens (vs. NE)
164) Matthew Golden, WR | Green Bay Packers (at CHI)
165) Cade Otton, TE | Tampa Bay Buccaneers (at CAR)
166) Isaiah Likely, TE | Baltimore Ravens (vs. NE)
167) Greg Dulcich, TE | Miami Dolphins (vs. CIN)
168) Keaton Mitchell, RB | Baltimore Ravens (vs. NE)
169) Dare Ogunbowale, RB | Houston Texans (vs. LV)
170) DeMario Douglas, WR | New England Patriots (at BAL)
171) Van Jefferson, WR | Tennessee Titans (vs. KC)
172) Keon Coleman, WR | Buffalo Bills (at CLE)
173) Jalen Nailor, WR | Minnesota Vikings (at NYG)
174) Jalen McMillan, WR | Tampa Bay Buccaneers (at CAR)
175) Brashard Smith, RB | Kansas City Chiefs (at TEN)

Baker Mayfield, QB, Tampa Bay Buccaneers (at CAR)

Somehow, Baker Mayfield reached 20 fantasy points last Thursday night. It certainly didn’t feel that way watching in real time.

Something is wrong with Mayfield. Perhaps there is an undisclosed injury affecting his play that we will find out about in the offseason. But he does not look right.

Nevertheless, Mayfield ham and egged his way to 20 fantasy points against the Falcons. It was just the fourth time he’s hit that marker all season. His 277 passing yards were his highest total since Week 5.

This is a huge matchup that may very well decide the NFC South, which has become a battle of who wants it less. Both the Tampa Bay Buccaneers and Carolina Panthers are coming off very bad losses. Someone is going to rebound. Unfortunately, for the Bucs, they’re the road team here.

The Panthers have not been the same pushover on defense they’ve been in previous years. They’re allowing the eighth-fewest fantasy points per game to quarterbacks. This has all the makings of an ugly, frustrating field goal fest.

Xavier Worthy | KC (at TEN)

Xavier Worthy doesn’t have a top 25 finish at the position since September, so it shouldn’t surprise you in the slightest that he’s off my radar this weekend with Gardner Minshew taking over under center.

The volume simply hasn’t been there at any point, and while the chunk plays were finally starting to come (25+ yard reception in four straight), the hopes of those chunk plays being stable vanished when Patrick Mahomes crumpled to the ground.

There’s a larger conversation this offseason about how his skill set fits into this offense (for the record, I think it can work, but maybe the Rashee Rice saga this summer affected the plans a bit). I’m tentatively bullish for 2026, but that doesn’t mean I’d suggest rolling him out there in anything but deeper formats for the remainder of this season.

And yes, “tentatively bullish” will be the name of any team I draft him on next season.

Zay Flowers | BAL (vs NE)

Zay Flowers can make some outstanding plays, but he showed us on Sunday that he can make the mundane look difficult, and that’s been part of the battle we’ve faced.

He’s the unquestioned lead in this passing game, and that projects to be the case for the remainder of this season and the foreseeable future, but he’s finished in that WR20-32 bucket in six of his past eight games, and that’s just not enough of a ceiling given his role.

Against the Bengals, he had a pass put in the perfect spot, and instead of snatching it, he let it eat him up, resulting in an interception off a deflection. That hurt, but then he reminded us of what is possible with a two-catch 54-yard drive that saw him score from 28 yards out to end the first half, his first trip to the end zone since Week 1.

But wait, there’s more.

Lamar Jackson was a little off on an end zone target to an open Flowers, but he catches it more often than not. It didn’t happen, and that left us with three receptions on five targets for the afternoon, but targets being impactful plays that should have been completed.

Ugh.

Flowers hasn’t caught more than four passes in four of his past six games, and while he’s likely to set a new career high in both receptions and yards this year, the growth has been minimal at best across his three seasons.

Will the light click in 2026?

I hope so. I expect this offense to function in a similar style, and that means the opportunity will be there. Even with some of the risk in terms of consistency, you’re playing him this week if for no other reason than it’s a motivated offense with the potential to get hot, even in a tougher matchup.

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