Week 6 of the fantasy football season has arrived, and it’s more important than ever to know which players deserve a place in your starting lineup. Considering player talent, recent form, and matchups, we’ve put together our PFSN consensus Week 6 RB rankings.
These rankings were last updated at 8:00 AM ET on Monday, October 06, 2025.
Week 6 RB Fantasy Rankings
1) Christian McCaffrey | San Francisco 49ers (at TB)
2) Bijan Robinson | Atlanta Falcons (vs. BUF)
3) Jahmyr Gibbs | Detroit Lions (at KC)
4) Jonathan Taylor | Indianapolis Colts (vs. ARI)
5) Saquon Barkley | Philadelphia Eagles (at NYG)
6) Josh Jacobs | Green Bay Packers (vs. CIN)
7) James Cook | Buffalo Bills (at ATL)
8) De’Von Achane | Miami Dolphins (vs. LAC)
9) Javonte Williams | Dallas Cowboys (at CAR)
10) Kyren Williams | Los Angeles Rams (at BAL)
11) Ashton Jeanty | Las Vegas Raiders (vs. TEN)
12) Derrick Henry | Baltimore Ravens (vs. LAR)
13) Rico Dowdle | Carolina Panthers (vs. DAL)
14) Quinshon Judkins | Cleveland Browns (at PIT)
15) Breece Hall | New York Jets (vs. DEN)
16) J.K. Dobbins | Denver Broncos (at NYJ)
17) Jacory Croskey-Merritt | Washington Commanders (vs. CHI)
18) Cam Skattebo | New York Giants (vs. PHI)
19) Rachaad White | Tampa Bay Buccaneers (vs. SF)
20) Alvin Kamara | New Orleans Saints (vs. NE)
21) Travis Etienne Jr. | Jacksonville Jaguars (vs. SEA)
22) Tony Pollard | Tennessee Titans (at LV)
23) D’Andre Swift | Chicago Bears (at WAS)
24) David Montgomery | Detroit Lions (at KC)
25) Jaylen Warren | Pittsburgh Steelers (vs. CLE)
26) Michael Carter | Arizona Cardinals (at IND)
27) Zach Charbonnet | Seattle Seahawks (at JAX)
28) Kenneth Walker III | Seattle Seahawks (at JAX)
29) Chase Brown | Cincinnati Bengals (at GB)
30) Rhamondre Stevenson | New England Patriots (at NO)
31) TreVeyon Henderson | New England Patriots (at NO)
32) Kenneth Gainwell | Pittsburgh Steelers (vs. CLE)
33) Kendre Miller | New Orleans Saints (vs. NE)
34) Justice Hill | Baltimore Ravens (vs. LAR)
35) Tyler Allgeier | Atlanta Falcons (vs. BUF)
36) Kareem Hunt | Kansas City Chiefs (vs. DET)
37) RJ Harvey | Denver Broncos (at NYJ)
38) Isiah Pacheco | Kansas City Chiefs (vs. DET)
39) Kimani Vidal | Los Angeles Chargers (at MIA)
40) Hassan Haskins | Los Angeles Chargers (at MIA)
41) Isaiah Davis | New York Jets (vs. DEN)
42) Bhayshul Tuten | Jacksonville Jaguars (vs. SEA)
43) Brashard Smith | Kansas City Chiefs (vs. DET)
44) Emari Demercado | Arizona Cardinals (at IND)
45) Chris Rodriguez Jr. | Washington Commanders (vs. CHI)
46) Ollie Gordon II | Miami Dolphins (vs. LAC)
47) Sean Tucker | Tampa Bay Buccaneers (vs. SF)
48) Blake Corum | Los Angeles Rams (at BAL)
49) Tyjae Spears | Tennessee Titans (at LV)
50) Kyle Monangai | Chicago Bears (at WAS)
Chase Brown, RB, Cincinnati Bengals
Like Henry, Cincinnati Bengals running back Chase Brown has been an enormous disappointment in fantasy this year. The entire Bengals offense has struggled following Joe Burrow’s Week 2 injury, with backup Jake Browning looking well below par.
Having won their opening two games of the season, the Bengals can still make the playoffs, despite their recent slump. After a considerable investment in their offensive weapons this past offseason, they can’t afford to be idle.
Browning got the offense moving late against the Detroit Lions in Week 5, but the entire second half felt like garbage time, given how poorly the Bengals were playing. Cincinnati needs to find a way to get Brown more involved, and if you can get him for mid to low-end RB2 value, he’s talented enough to bet on.
TreVeyon Henderson, RB, New England Patriots
It’s only a matter of time until TreVeyon Henderson gets a real opportunity to blow up in fantasy football. Currently, it seems that, regardless of how many times he fumbles the ball, Rhamondre Stevenson will continue to receive the best opportunities for the New England Patriots.
However, that won’t last forever, and Henderson is explosive enough to force the team to feed him sooner or later. It’s not unusual for rookies to be introduced slowly, and nobody should be panicking about the former Ohio State star just yet.
Antonio Gibson left Week 5’s game against the Buffalo Bills with a knee injury, which could help Henderson’s cause moving forward. Upcoming games against the New Orleans Saints and Tennessee Titans should offer the rookie an excellent opportunity to earn a starting role.
Henderson should be pursued at a mid-to-low-end RB2 value, and will be a weekly RB1 contender when he finally takes over in New England.
