Week 16 of the fantasy football season has arrived, and it’s more important than ever to know which players deserve a place in your starting lineup. Considering player talent, recent form, and matchups, we’ve put together our PFSN consensus Week 16 FLEX rankings.
These rankings were last updated at 7:00 AM ET on Monday, December 15, 2025.
Week 16 Top Fantasy FLEX Rankings
1) Puka Nacua, WR | Los Angeles Rams (at SEA)
2) Ja’Marr Chase, WR | Cincinnati Bengals (at MIA)
3) Christian McCaffrey, RB | San Francisco 49ers (at IND)
4) Jahmyr Gibbs, RB | Detroit Lions (vs. PIT)
5) Bijan Robinson, RB | Atlanta Falcons (at ARI)
6) Jaxon Smith-Njigba, WR | Seattle Seahawks (vs. LAR)
7) Amon-Ra St. Brown, WR | Detroit Lions (vs. PIT)
8) De’Von Achane, RB | Miami Dolphins (vs. CIN)
9) Nico Collins, WR | Houston Texans (vs. LV)
10) Michael Wilson, WR | Arizona Cardinals (vs. ATL)
11) CeeDee Lamb, WR | Dallas Cowboys (vs. LAC)
12) James Cook, RB | Buffalo Bills (at CLE)
13) Mike Evans, WR | Tampa Bay Buccaneers (at CAR)
14) Jaylen Waddle, WR | Miami Dolphins (vs. CIN)
15) Trey McBride, TE | Arizona Cardinals (vs. ATL)
16) Josh Jacobs, RB | Green Bay Packers (at CHI)
17) A.J. Brown, WR | Philadelphia Eagles (at WAS)
18) Saquon Barkley, RB | Philadelphia Eagles (at WAS)
19) Jonathan Taylor, RB | Indianapolis Colts (vs. SF)
20) Chase Brown, RB | Cincinnati Bengals (at MIA)
21) Jameson Williams, WR | Detroit Lions (vs. PIT)
22) Travis Etienne Jr., RB | Jacksonville Jaguars (at DEN)
23) Rashee Rice, WR | Kansas City Chiefs (at TEN)
24) George Kittle, TE | San Francisco 49ers (at IND)
25) TreVeyon Henderson, RB | New England Patriots (at BAL)
26) George Pickens, WR | Dallas Cowboys (vs. LAC)
27) Tetairoa McMillan, WR | Carolina Panthers (vs. TB)
28) DK Metcalf, WR | Pittsburgh Steelers (at DET)
29) Chris Olave, WR | New Orleans Saints (vs. NYJ)
30) Bucky Irving, RB | Tampa Bay Buccaneers (at CAR)
31) Javonte Williams, RB | Dallas Cowboys (vs. LAC)
32) Jauan Jennings, WR | San Francisco 49ers (at IND)
33) RJ Harvey, RB | Denver Broncos (vs. JAX)
34) Derrick Henry, RB | Baltimore Ravens (vs. NE)
35) D’Andre Swift, RB | Chicago Bears (vs. GB)
36) Kyle Pitts Sr., TE | Atlanta Falcons (at ARI)
37) Kyren Williams, RB | Los Angeles Rams (at SEA)
38) Aaron Jones Sr., RB | Minnesota Vikings (at NYG)
39) Terry McLaurin, WR | Washington Commanders (vs. PHI)
40) Quinshon Judkins, RB | Cleveland Browns (vs. BUF)
41) Breece Hall, RB | New York Jets (at NO)
42) Zay Flowers, WR | Baltimore Ravens (vs. NE)
43) Ladd McConkey, WR | Los Angeles Chargers (at DAL)
44) Jakobi Meyers, WR | Jacksonville Jaguars (at DEN)
45) Brock Bowers, TE | Las Vegas Raiders (at HOU)
46) Tyrone Tracy Jr., RB | New York Giants (vs. MIN)
47) Courtland Sutton, WR | Denver Broncos (vs. JAX)
48) Chris Godwin, WR | Tampa Bay Buccaneers (at CAR)
49) Wan’Dale Robinson, WR | New York Giants (vs. MIN)
50) Brian Thomas Jr., WR | Jacksonville Jaguars (at DEN)
51) DJ Moore, WR | Chicago Bears (vs. GB)
52) DeVonta Smith, WR | Philadelphia Eagles (at WAS)
53) Michael Pittman Jr., WR | Indianapolis Colts (vs. SF)
54) Omarion Hampton, RB | Los Angeles Chargers (at DAL)
55) Rico Dowdle, RB | Carolina Panthers (vs. TB)
56) Travis Kelce, TE | Kansas City Chiefs (at TEN)
57) Dallas Goedert, TE | Philadelphia Eagles (at WAS)
58) Jaylen Warren, RB | Pittsburgh Steelers (at DET)
59) Stefon Diggs, WR | New England Patriots (at BAL)
60) Tony Pollard, RB | Tennessee Titans (vs. KC)
61) Michael Carter, RB | Arizona Cardinals (vs. ATL)
62) Ashton Jeanty, RB | Las Vegas Raiders (at HOU)
63) Deebo Samuel Sr., WR | Washington Commanders (vs. PHI)
64) Emeka Egbuka, WR | Tampa Bay Buccaneers (at CAR)
65) Jordan Addison, WR | Minnesota Vikings (at NYG)
66) Jayden Reed, WR | Green Bay Packers (at CHI)
67) Rhamondre Stevenson, RB | New England Patriots (at BAL)
68) Jawhar Jordan, RB | Houston Texans (vs. LV)
69) Khalil Shakir, WR | Buffalo Bills (at CLE)
70) Tyler Warren, TE | Indianapolis Colts (vs. SF)
71) Zach Charbonnet, RB | Seattle Seahawks (vs. LAR)
72) Adonai Mitchell, WR | New York Jets (at NO)
73) Kenneth Walker III, RB | Seattle Seahawks (vs. LAR)
74) Kimani Vidal, RB | Los Angeles Chargers (at DAL)
75) Chuba Hubbard, RB | Carolina Panthers (vs. TB)
76) Kenneth Gainwell, RB | Pittsburgh Steelers (at DET)
77) Keenan Allen, WR | Los Angeles Chargers (at DAL)
78) Harold Fannin Jr., TE | Cleveland Browns (vs. BUF)
79) Colby Parkinson, TE | Los Angeles Rams (at SEA)
80) Romeo Doubs, WR | Green Bay Packers (at CHI)
81) Kyle Monangai, RB | Chicago Bears (vs. GB)
82) Kareem Hunt, RB | Kansas City Chiefs (at TEN)
83) Blake Corum, RB | Los Angeles Rams (at SEA)
84) Xavier Worthy, WR | Kansas City Chiefs (at TEN)
85) Dalton Schultz, TE | Houston Texans (vs. LV)
86) Jayden Higgins, WR | Houston Texans (vs. LV)
87) David Montgomery, RB | Detroit Lions (vs. PIT)
88) Troy Franklin, WR | Denver Broncos (vs. JAX)
89) Jerry Jeudy, WR | Cleveland Browns (vs. BUF)
90) Alec Pierce, WR | Indianapolis Colts (vs. SF)
91) Kayshon Boutte, WR | New England Patriots (at BAL)
92) Devin Singletary, RB | New York Giants (vs. MIN)
93) Jalen Coker, WR | Carolina Panthers (vs. TB)
94) Darius Slayton, WR | New York Giants (vs. MIN)
95) Justin Jefferson, WR | Minnesota Vikings (at NYG)
96) Jacory Croskey-Merritt, RB | Washington Commanders (vs. PHI)
97) Tyler Allgeier, RB | Atlanta Falcons (at ARI)
98) Devaughn Vele, WR | New Orleans Saints (vs. NYJ)
99) Dalton Kincaid, TE | Buffalo Bills (at CLE)
100) Chimere Dike, WR | Tennessee Titans (vs. KC)
Baker Mayfield, QB, Tampa Bay Buccaneers (at CAR)
Somehow, Baker Mayfield reached 20 fantasy points last Thursday night. It certainly didn’t feel that way watching in real time.
Something is wrong with Mayfield. Perhaps there is an undisclosed injury affecting his play that we will find out about in the offseason. But he does not look right.
Nevertheless, Mayfield ham and egged his way to 20 fantasy points against the Falcons. It was just the fourth time he’s hit that marker all season. His 277 passing yards were his highest total since Week 5.
This is a huge matchup that may very well decide the NFC South, which has become a battle of who wants it less. Both the Tampa Bay Buccaneers and Carolina Panthers are coming off very bad losses. Someone is going to rebound. Unfortunately, for the Bucs, they’re the road team here.
The Panthers have not been the same pushover on defense they’ve been in previous years. They’re allowing the eighth-fewest fantasy points per game to quarterbacks. This has all the makings of an ugly, frustrating field goal fest.
Caleb Williams, QB, Chicago Bears (vs. GB)
Caleb Williams being so heavily rostered is quite curious. How many usable weeks has he given fantasy managers this season? If you’re extra generous, you can get to eight, maybe nine. Basically, about half the time, Williams is worth starting.
That’s because he’s the most predictable quarterback in fantasy. Give him a good matchup and he will excel. Give him a bad matchup and he will disappoint.
We already saw Williams against the Green Bay Packers a mere two weeks ago. He posted just under 16 fantasy points. Williams failed to reach 200 yards through the air and provided just 15 yards on the ground.
If around 15 fantasy points is good enough for you, then by all means, fire up Williams. But if you’re looking for QB1 upside, Williams is best left on benches.
