The Cleveland Browns will host the Buffalo Bills in Week 16. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, specifically regarding RB Dylan Sampson.
Is Sampson Playing in Week 16?
Sampson (hand/calf) has been ruled out for Sunday’s game against the Bills, Mary Kay Cabot of the Cleveland Plain Dealer reports.
We’ll continue to monitor the Browns’ injury report leading up to kickoff for any changes. You can also visit and bookmark our Fantasy News Tracker for the latest updates.
Should You Start or Sit Sampson in Week 16?
With Jerome Ford on IR, you could have made the case for Dylan Sampson as an end-of-bench type with the thought being that he was a Quinshon Judkins injury away from handling enough work to at least be moderately interesting.
The rookie sat out last week with what we thought was a calf injury, but saw “hand” added to the description on Wednesday. Regardless of exactly what is ailing him, at 2.6 yards per carry, it’s hard to imagine him being a valuable asset even if he did happen to fall into volume with the season nearing its conclusions.
His savvy out of the backfield (28 catches on 34 targets for 259 yards and two scores) is an interesting skill set to carry into 2026 and could make him a late round stash, but for the remainder of this season, there’s no need to hold.
Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.
Sampson’s Fantasy Points Projection in Week 16
Sampson is projected to score 0.0 points in PPR formats. This includes 0.0 receptions for 0.0 yards and 0.0 touchdowns.
Check out the free PFSN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.
Week 16 Weather Impact: Bills at Browns
The forecast for kickoff is 25 degrees Fahrenheit with 16 mph winds. Moderate winds may affect deep passes and field goal attempts.
