The Arizona Cardinals will host the Jacksonville Jaguars in Week 12 as they look to notch just their second win in eight weeks. Jacksonville, meanwhile, aims to build on the momentum from last week’s convincing 35-6 victory over the Chargers.
Both teams dealt with numerous injury designations throughout the week, and several key players, including Marvin Harrison Jr. and Trey Benson, have been ruled out. Here’s a closer look at the full injury report.
Who Are Out of Contention for the Jacksonville Jaguars?
Brian Thomas Jr. will miss his third straight game, still recovering from the injury he sustained in Week 9 against the Raiders.
However, NFL Network’s Tom Pelissero reported that he has a “good chance” of playing in Week 13.
Tight end Hunter Long also remains out, still dealing with the knee issue suffered in Week 9.
Jacksonville has clearly felt the loss of his size and physicality, particularly in two-tight end sets. Fortunately, Brenton Strange’s return helps offset Long’s absence if he’s able to suit up.
Pelissero: Brian Thomas Jr. (ankle) has “good chance” to play Week 13.
— Underdog NFL (@UnderdogNFL) November 23, 2025
The Jaguars will also be without right tackle Anton Harrison and linebacker Yasir Abdullah, further thinning their rotation.
- LB Yasir Abdullah (finger) – OUT
- RT Anton Harrison (knee/ankle) – OUT
- TE Hunter Long (hip/knee) – OUT
- WR Brian Thomas Jr. (ankle) – OUT
- DE Travon Walker (knee) – OUT
- CB Jarrian Jones (quadriceps) – Questionable
- CB Jourdan Lewis (neck) – Questionable
- TE Brenton Strange (hip) – Questionable
Arizona Cardinals Week 12 Injury Report
The Cardinals will continue to be without Marvin Harrison Jr., who underwent an appendectomy following their Week 10 loss to the Seahawks. Arizona will also be without running backs Trey Benson and Emari Demercado, as well as James Conner, who’s ruled out for the season.
Benson practiced in a limited capacity throughout the week but is not yet cleared for game action, while Demercado missed the entire week of practice due to an ankle injury. That leaves Bam Knight, who practiced fully on Friday, along with practice-squad call-ups to handle the backfield workload.
Defensively, Baron Browning and Dadrion Taylor-Demerson will miss their second consecutive game. Browning remains in concussion protocol. while Taylor Demerson nurses his ankle injury.
- RB Trey Benson (knee/practicing while on IR) – OUT
- LB Baron Browning (concussion) – OUT
- RB Emari Demercado (ankle) – OUT
- WR Marvin Harrison Jr. (illness) – OUT
- S Dadrion Taylor-Demerson (ankle) – OUT
- RT Kelvin Beachum (groin) – Questionable
- C/G Hayden Conner (knee/practicing while on IR) – Questionable
- RG Will Hernandez (knee) – Questionable
- CB Will Johnson (back/hip) – Questionable
- DL Darius Robinson (groin) – Questionable
- CB Garrett Williams (ankle) – Questionable
Arizona also currently has Kyler Murray (foot), running back duo Conner and Benson, receiver Zay Jones (Achilles), tackle Jonah Williams (shoulder), and linebacker Mack Wilson (ribs) on injured reserve. Jacksonville has only rookie cornerback Travis Hunter on IR entering the matchup.
Kickoff from State Farm Stadium is scheduled for 4:05 p.m. ET today, November 23.
