The first Sunday of the NFL season is ending on a high note, as the Baltimore Ravens travel to Buffalo to take on the Bills at Highmark Stadium. Our preview has you covered with game info, matchup history, PFSN player grades, and a prediction.
Bills vs Ravens Details
Date: Sunday, September 7, 2025
Game Time: 8:20 p.m. ET
Location: Highmark Stadium, Orchard Park, NY
Predicted Weather at Kick: 47 degrees, partly cloudy, 25% rain probability
How to Watch: NBC, Peacock
Bills vs Ravens Head-to-Head Record
The Ravens hold the regular-season head-to-head advantage over the Bills with a 7-4 record, but Buffalo has the advantage in the postseason with a 2-0 record.
This is a rematch of last season’s Divisional Round matchup in Buffalo, where the Bills won a 27-25 thriller that ended on a Mark Andrews dropped pass on a game-tying two-point conversion attempt.
The two-point conversion is no good 😳
📺: #BALvsBUF on CBS
📱: Stream on @NFLPlus and Paramount+ pic.twitter.com/s1DAo0tdm1— NFL (@NFL) January 20, 2025
Baltimore dominated Buffalo 35-10 in their regular-season matchup last year in Buffalo. In the regular season, the Ravens hold a 2-1 advantage in games started by Lamar Jackson and Josh Allen. Those two quarterbacks are the last two NFL MVP winners and were the top two vote-getters last year.
Bills vs Ravens Grades
Below are the PFSN team and positional grades from 2024 for the highest-ranked returning players set to be featured on Sunday night.
PFSN NFL OFF+Â
Baltimore Ravens (93.6, A)
Buffalo Bills (88.6, B+)
PFSN NFL DEF+Â
Baltimore Ravens (79.3, C+)
Buffalo Bills (72.0, C-)
PFSN NFL Team OL+
Baltimore Ravens (86.18, B)
Buffalo Bills (81.24, B-)
PFSN NFL Team ST+Â
Buffalo Bills (77.6, C+)
Baltimore Ravens (74.3, C)
PFSN NFL QB+
Lamar Jackson, Ravens (96.3, A)
Josh Allen, Bills (90.8, A)
PFSN NFL RB+
Derrick Henry, Ravens (93.1, A)
James Cook, Bills (84.3, B)
PFSN NFL WR+Â
Khalil Shakir, Bills (86.6, B)
Zay Flowers, Ravens (83.3, B)
PFSN NFL TE+
Mark Andrews, Ravens (84.40, B)
Dalton Kincaid, Bills (76.73, C)
PFSN NFL Ind OL+
Tyler Linderbaum, Ravens (93.21, A)
Spencer Brown, Bills, (87.88)
PFSN NFL EDGE +
Greg Rousseau, Bills (87.47, B+)
Kyle Van Noy (77.95, C+)
PFSN NFL DT +
Nnamdi Madubuike, Ravens (85.61, B)
Ed Oliver, Bills (79.84, C+)
PFSN NFL LB +
Roquan Smith, Ravens (87.25, B+)
Terrel Bernard, Bills (77.93, C+)
PFSN NFL CB +
Christian Benford, Bills (88.56, B+)
Marlon Humphrey, Ravens (85.76, B)
PFSN NFL SAF+
Kyle Hamilton, Ravens (83.05, B)
Taylor Rapp, Bills (80.96, B-)
Bills vs Ravens Prediction
We all know the headline for this one. Jackson and Allen are the last two MVP winners and two of the most entertaining quarterbacks ever to play the game. They lead two of the best teams in the league that have yet to get over the Super Bowl hump.
This might be the most entertaining regular-season matchup possible in today’s NFL, and the league gave the fans a gift by making this the Week One Sunday Night game. But as otherworldly as the two starting quarterbacks are, recent matchups between the two teams have come down to the other players.
In last year’s 35-10 Ravens Sunday Night demolition of Buffalo, Lamar Jackson played as much of a supporting role as a quarterback who averaged 0.39 EPA/Play while accounting for three total touchdowns. Derrick Henry started off the game with an 87-yard touchdown run on the first play and finished with 199 yards rushing.
DERRICK HENRY TO THE HOUSE!!!!!!!!!!
Tune in on NBC! pic.twitter.com/rRDLQvKh8P
— Baltimore Ravens (@Ravens) September 30, 2024
As a team, Baltimore ran the ball 34 times for 271 yards, while Lamar Jackson threw the ball just 19 times. The Bills had similar difficulties stopping the Ravens in the playoffs, relying largely on turnovers and self-inflicted Ravens wounds to win.
Defense was a bigger issue for the Bills last year, as a unit that had typically been towards the top of the league in the Allen era took a step backwards to being just slightly above average, finishing 12th in EPA/Play. The Bills aggressively worked on improving that side of the ball in the offseason, using their five draft picks on defense while bringing in veterans Tre’Davious White and Joey Bosa to help provide stability.
But first-round cornerback Maxwell Hairston is on the injured reserve, leaving the cornerback room outside of All-Pro Christian Benford a major question mark.
On the other side of the ball, Buffalo relied largely on the running game to move the ball in the playoff win. Ravens Defensive Coordinator Zachary Orr called perhaps his best game of the year in the Week Four matchup, with his simulated pressures and disguised blitzes on passing downs holding Buffalo to just 3-13 on third down. The Bills wanted to stay out of third-and-long, and figured the best way to do so was by taking advantage of their elite offensive line.
The fact that neither quarterback has unveiled their full share of magic tricks in recent matchups makes projecting this matchup difficult, as both are liable to do so at any given moment. In many ways, the Ravens vs Bills matchup is an unfinished product, waiting to reach its highest potential.
With the caveat that either quarterback can put on the Superman cape and win the game themselves, the rest of Baltimore’s roster is better than Buffalo’s. The only matchup where the Bills might have an advantage is their offensive line against the Ravens’ defensive front.
What’s more, the Ravens have the benefit of having more defensive continuity early in the season. While a Josh Allen superhero performance or a Ravens implosion are possible, Baltimore has more paths to winning this game than Buffalo.
Prediction: Ravens 27 – Bills 24
