NFL Week 5 Betting Lines: Early Odds for Each Game Next Week

Well, it’s official. We are now a quarter through the NFL season, and it was another Sunday that didn’t disappoint. If you tailed me on X, you went a stellar 22-6, all thanks to the great info found on PFN and PFN Betting — two accounts you need to follow on a daily basis.

Let’s dig into some of the day’s action before getting into the NFL Week 5 betting lines that just came out.

Some of today’s highlights include the fact that five teams didn’t score a touchdown, three of which are in the AFC North (Cincinnati Bengals, Cleveland Browns, Pittsburgh Steelers, New England Patriots, and New Orleans Saints). We also saw the Buffalo Bills establish their dominance of the NFL with a blowout victory over the Miami Dolphins.

The Philadelphia Eagles allowed the Washington Commanders to claw their way back into today’s game, forcing overtime, which D.C. eventually lost. We also saw the Indianapolis Colts do the same in their game vs. the Los Angeles Rams. They also forced OT, which they eventually lost — two teams who put in all that effort for nothing.

MORE: Live Betting Odds and Newest Promos

The NFL also saw QB Brock Purdy and the San Francisco 49ers cover today’s largest spread (-14.5, -15.5 at kickoff) with a 35-16 victory.

There is still one more game tomorrow night between the Seattle Seahawks and New York Giants — a game that doesn’t look like fireworks on the surface, but QB Geno Smith can produce magic, especially in prime time.

Looking ahead to the NFL Week 5 betting lines, we have yet to get a double-digit favorite. The closest we have so far is the Detroit Lions as -8.5 favorites against the Carolina Panthers and the Miami Dolphins as -9.5 favorites over the New York Giants. I expect at least the Dolphins line to get into double-digit territory by Sunday.

We also have five games with lines less than three points, so you can expect to see some close contests next week.

We’ll give out our early predictions and picks against the spread tomorrow, but in the meantime, let’s take a look at the opening NFL Week 5 betting lines.

Our Betting Lines page has the freshest lines and promos to get BANG for your buck. PFN’s FREE Parlay Calculator and Betting Odds Calculator are also available for your betting process! New to sports betting? Check out our guide on How to Bet on the NFL. Visit our Sports Betting Legal Tracker on how to bet legally in the U.S.

NFL Week 5 Betting Lines

All odds are from FanDuel Sportsbook.

Chicago Bears vs. Washington Commanders Odds

  • Spread
    Commanders -5.5
  • Moneyline
    Commanders -260, Bears +215
  • Total
    44.5

Jacksonville Jaguars vs. Buffalo Bills Odds

  • Spread
    Bills -5.5
  • Moneyline
    Bills -220, Jaguars +184
  • Total
    48

Houston Texans vs. Atlanta Falcons Odds

  • Spread
    Falcons -2.5
  • Moneyline
    Falcons -142, Texans +120
  • Total
    44

Carolina Panthers vs. Detroit Lions Odds

  • Spread
    Lions -8.5
  • Moneyline
    Lions -430, Panthers +340
  • Total
    44

Tennessee Titans vs. Indianapolis Colts Odds

  • Spread
    Colts -1.5
  • Moneyline
    Colts -112, Titans -104
  • Total
    41.5

New York Giants vs. Miami Dolphins Odds

  • Spread
    Dolphins -9.5
  • Moneyline
    Dolphins -510, Giants +390
  • Total
    49.5

Pittsburgh Steelers vs. Baltimore Ravens Odds

  • Spread
    Ravens -3.5
  • Moneyline
    Ravens -176, Steelers +148
  • Total
    40.5

New Orleans Saints vs. New England Patriots Odds

  • Spread
    Patriots -1.5
  • Moneyline
    Patriots -116, Saints -102
  • Total
    39

Cincinnati Bengals vs. Arizona Cardinals Odds

  • Spread
    Bengals -4.5
  • Moneyline
    Bengals -196, Cardinals +164
  • Total
    42.5

Philadelphia Eagles vs. Los Angeles Rams Odds

  • Spread
    Eagles -5.5
  • Moneyline
    Eagles -225, Rams +188
  • Total
    46.5

Kansas City Chiefs vs. Minnesota Vikings Odds

  • Spread
    Chiefs -6
  • Moneyline
    Chiefs -270, Vikings +220
  • Total
    53

New York Jets vs. Denver Broncos Odds

  • Spread
    Broncos -2.5
  • Moneyline
    Broncos -144, Jets +122
  • Total
    40

Dallas Cowboys vs. San Francisco 49ers Odds

  • Spread
    49ers -3.5
  • Moneyline
    49ers -174, Cowboys +146
  • Total
    43.5

Green Bay Packers vs. Las Vegas Raiders Odds

  • Spread
    Packers -1.5
  • Moneyline
    Packers -112, Raiders -104
  • Total
    43.5

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