The Kansas City Chiefs will face the Carolina Panthers in Week 12. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, especially regarding QB Patrick Mahomes.
Is Patrick Mahomes Playing in Week 12?
Mahomes is not listed on the injury report this week, so barring any setbacks, he is on track to play this weekend.
We’ll continue to monitor the Chiefs’ injury report. You can also visit and bookmark our NFL Injury Tracker and Fantasy News Tracker for the latest updates.
Should You Start or Sit Patrick Mahomes in Week 12?
Patrick Mahomes can be the most feared quarterback in real life while also being an afterthought in our game, and that is the space in which he is currently living. What do these quarterbacks have in common?
- Anthony Richardson
- Daniel Jones
- Justin Fields
Yes, they’ve all been benched this season, that’s factually accurate. But they all also have more top-10 finishes this season than Mahomes, how crazy is that?
It goes without saying that nothing about this matchup is intimidating, but the flaws that have presented themselves all season long could be magnified on Sunday — the need for big numbers. With Kansas City a double-digit road favorite, there’s even more risk than normal that No. 15 won’t be relied on at the rate we need. I have Mahomes ranked as my QB12 this week, putting him right on the fringe.
- QB9: Bo Nix (at LV)
- QB10: Baker Mayfield (at NYG)
- QB11: Tua Tagovailoa (vs. NE)
- QB12: Patrick Mahomes (at CAR)
- QB13: Jordan Love (vs. SF)
- QB14: Drake Maye (at MIA)
Are you looking for start/sit advice for other players in your lineup? Read our Week 12 Fantasy Start-Sit Advice Cheat Sheet for every fantasy-relevant player in every game.
Patrick Mahomes’ Fantasy Points Projection in Week 12
As of early Sunday morning, Mahomes is projected to score 17.9 fantasy points in Week 12. This includes 237.5 passing yards, 1.7 passing touchdowns, and 0.8 interceptions. It also includes 3.6 rushing attempts for 18.7 yards and 0.1 touchdowns.
Check out the free PFN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.
PFN Insight on the Bills' Defense
After finishing as a top-seven defense in each of the last three seasons, the Bills finished 18th during the regular season. That's not the biggest surprise given that this was largely billed as a rebuilding season for this unit.
Buffalo was a boom-or-bust defense in the Divisional Round vs. Baltimore, and there were just enough highs to escape with the win. In addition to the three takeaways, the Bills also generated their second-highest non-blitz pressure rate (42.9%) this season. The only higher rate was in the Wild Card win over the Broncos (50%).
This wasn't a particularly efficient defensive performance, as reflected in the final Defense+ grade of 69.9 (D+). Despite some run stuffs, the Bills had their worst rushing defense success rate all season (44%) and were fortunate the game script didn't allow the Ravens to lean more heavily on their run game.
Still, the Bills' offense is operating at such a high level that the bar to clear for the defense is lower than it would be on nearly any other team. Buffalo met that threshold with a few big plays against the Ravens. Those could be tougher to generate against a Chiefs offense that has gone eight straight games without a turnover, but it may be all the Bills need to finally conquer Kansas City.
For more insight on all other team defenses, head to our PFN Defense+ Metric Analysis.Â
Patrick Mahomes’ Fantasy Ranking
Our Weekly Consensus PPR Rankings are below — both positional and overall. They were last updated at 11:45 PM ET on Saturday, January 25.Â
Conference Championship QB PPR Rankings
1) Josh Allen | BUF (at KC)
2) Jalen Hurts | PHI (vs. WAS)
3) Jayden Daniels | WAS (at PHI)
4) Patrick Mahomes | KC (vs. BUF)
Bills at Chiefs Trends and Insights
Buffalo Bills
Team: The Bills lost four road games during the regular season — only four Super Bowl champions in the 2000s have done that (2018 Patriots, 2012 Ravens, 2010 Packers, and 2006 Colts).
QB: Five times has a QB had four games in a season (playoffs included) with multiple rush touchdowns and 20 pass attempts.
- 2021 Jalen Hurts
- 2022 Jalen Hurts
- 2023 Jalen Hurts
- 2023 Josh Allen
- 2024 Josh Allen
No player has had five such games in a season.
Offense: The Bills have scored on at least 55% of their possessions six times this season, four of which have come against playoff teams.
Defense: Buffalo allowed Baltimore to pick up 70% of their third downs. That’s the fourth-highest rate the Bills have allowed in the 2000s and is their highest in a winning effort.
Fantasy: Allen has completed over 72% of his passes in both playoff wins – he had three such games during the regular season.
Betting: Overs are 5-2 in Buffalo’s past seven games, cashing last week by half a point with Baltimore's final touchdown.
Kansas City Chiefs
Team: Christmas Day 2023 was the date of Kansas City’s last home loss – each of their past six Arrowhead games have been decided by a single possession.
QB: Patrick Mahomes has thrown a total of three touchdown passes in his last two Championship games (3.7% of his attempts) after throwing three in each of his first four appearances (8.4%).
Offense: Saturday was the 10th time this season in which the Chiefs scored on at least half of their possessions (five-of-nine against Houston).
Defense: Opponents have picked up at least half of their third downs in four straight games against the Chiefs (Texans: 10-of-17).
Fantasy: In the last two games in which their starters have been extended, the Chiefs have managed to turn 42 carries into just 119 yards (2.83 yards per carry).
Betting: By taking an intentional safety at the end of their win over the Texans, the Chiefs snapped their six-game playoff cover streak.

