NFL Week 1 Odds, Spreads, and Betting Trends for Every Game

Don't lock in your betting card just yet. We have you covered with the NFL Week 1 odds and betting trends for the slate to help you make your picks!

We did it! We’ve been waiting seven-plus months, but we made it: our first NFL Sunday is here! What better way to welcome in the new season than breaking down the NFL Week 1 odds and spreads, plus giving you a betting trend for each game to put you in a position to not only enjoy this week but profit?

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NFL Week 1 Odds and Betting Trends

All odds are from DraftKings Sportsbook and trends from Inside Edge. Click on the widget for each game to place your bet.

Carolina Panthers vs. Atlanta Falcons

  • Spread
    Falcons -3.5
  • Moneyline
    Panthers +154, Falcons -185
  • Total
    39.5

Trend: The Panthers are a league-worst 4-12 ATS over the past two seasons in games that go over the projected total.

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:carolina-panthers-atlanta-falcons/variant:2?id=f5f14cb7-bc82-406e-9b06-585a94a8e36e”]

Cincinnati Bengals vs. Cleveland Browns

  • Spread
    Bengals -2
  • Moneyline
    Bengals -130, Browns +110
  • Total
    47.5

Trend: The Bengals are the best road team ATS over the past two seasons (13-4, CLE is 7-10 ATS at home).

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:cincinnati-bengals-cleveland-browns/variant:2?id=58ee80dc-dc8f-4f0a-8fbb-cf4e62b03bdb”]

Jacksonville Jaguars vs. Indianapolis Colts

  • Spread
    Jaguars -4.5
  • Moneyline
    Jaguars -230, Colts +190
  • Total
    46

Trend: Since 2020, no team is worse ATS as a favorite than the Jags (1-7, 12.5%).

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:jacksonville-jaguars-indianapolis-colts/variant:2?id=e232fcfd-3676-4be9-b0d2-f1bbc24e3092″]

Tampa Bay Buccaneers vs. Minnesota Vikings

  • Spread
    Vikings -5
  • Moneyline
    Buccaneers +180, Vikings -218
  • Total
    46

Trend: Overs are 22-12 in Vikings games over the past two seasons (64.7%, highest in the NFL)

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:tampa-bay-buccaneers-minnesota-vikings/variant:2?id=16d512f8-e426-4b14-8168-10875ad17e91″]

Tennessee Titans vs. New Orleans Saints

  • Spread
    Saints -3
  • Moneyline
    Titans +124, Saints -148
  • Total
    42

Trend: Since 2021, the Titans are 11-5 ATS when catching points (64.7%).

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:tennessee-titans-new-orleans-saints/variant:2?id=49fe1222-0b9e-4ddb-89e1-e42354415209″]

San Francisco 49ers vs. Pittsburgh Steelers

  • Spread
    49ers -2
  • Moneyline
    49ers -130, Steelers +110
  • Total
    41.5

Trend: Unders are 13-5 over the past two seasons when the Steelers cover (72.2%, highest in the NFL).

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:san-francisco-49-ers-pittsburgh-steelers/variant:2?id=b3e22e3d-a130-42f0-a670-24414b26f182″]

Arizona Cardinals vs. Washington Commanders

  • Spread
    Commanders -7
  • Moneyline
    Cardinals +270, Commanders -340
  • Total
    38

Trend: Since 2021, unders are 13-4 in Washington home games (76.5%, tied for the highest rate in the NFL).

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:arizona-cardinals-washington-commanders/variant:2?id=08cac7bc-2fc4-4b9e-a8fb-3b50ad86b4a9″]

Houston Texans vs. Baltimore Ravens

  • Spread
    Ravens -9.5
  • Moneyline
    Texans +370, Ravens -485
  • Total
    44

Trend: The Texans are a league-best 11-3-1 ATS (78.6%) over the past two seasons when the game goes over the projected total.

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:houston-texans-baltimore-ravens/variant:2?id=63fc136d-31ee-45b2-92e3-3b7413bbc9f9″]

Green Bay Packers vs. Chicago Bears

  • Spread
    Bears -1
  • Moneyline
    Packers -102, Bears -118
  • Total
    41.5

Trend: The Bears are 2-10 ATS over the past two seasons when playing within their division.

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:green-bay-packers-chicago-bears/variant:2?id=4dc96401-6b96-42a1-9545-c53c28157438″]

Las Vegas Raiders vs. Denver Broncos

  • Spread
    Broncos -3.5
  • Moneyline
    Raiders +145, Broncos -175
  • Total
    43.5

Trend: Unders were 6-3 in Raiders road games last season (66.7%, tied for the highest rate).

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:las-vegas-raiders-denver-broncos/variant:2?id=27a34c6b-1662-4b52-9e25-394c9788ec04″]

Philadelphia Eagles vs. New England Patriots

  • Spread
    Eagles -3.5
  • Moneyline
    Eagles -185, Patriots +154
  • Total
    44.5

Trend: No team was worse ATS on the road last season than the reigning NFC champions (2-6, 25%).

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:philadelphia-eagles-new-england-patriots/variant:2?id=db7c61a7-3ac1-405a-92c5-e0117e4c9868″]

Miami Dolphins vs. Los Angeles Chargers

  • Spread
    Chargers -3
  • Moneyline
    Dolphins +140, Chargers -166
  • Total
    51

Trend: Overs went 7-2 last season when on the Dolphins were on the road (1-7 when playing at home).

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:miami-dolphins-los-angeles-chargers/variant:2?id=32c00111-ca7d-42d6-b138-0e1b4bec668a”]

Los Angeles Rams vs. Seattle Seahawks

  • Spread
    Seahawks -5
  • Moneyline
    Rams +185, Seahawks -225
  • Total
    46

Trend: At 1-5, the Seahawks were the fifth-worst ATS team last season when favored.

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:los-angeles-rams-seattle-seahawks/variant:2?id=fa0accd6-a5ae-467f-84aa-4282cb02ffc7″]

Dallas Cowboys vs. New York Giants

  • Spread
    Cowboys -3
  • Moneyline
    Cowboys -170, Giants +142
  • Total
    45

Trend: Over the past two seasons, 11 teams have a winning ATS record at home: the Giants are the only one playing at home in Week 1.

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:dallas-cowboys-new-york-giants/variant:2?id=903ea258-e9a8-4501-8b22-2ed290971997″]

Buffalo Bills vs. New York Jets

  • Spread
    Bills -2.5
  • Moneyline
    Bills -135, Jets +114
  • Total
    45.5

Trend: Even without Aaron Rodgers last season, the Jets were 6-0 outright against top-10 pass defenses.

[tallysight url=”https://tallysight.com/new/widget/tile/nfl/org:pro-football-network/event:2023-24-week-1/topic:buffalo-bills-new-york-jets/variant:2?id=751a17fa-5aed-4f40-8c88-1207438bc981″]

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