Week 6 Fantasy WR Rankings: Start-Sit Advice for Brian Thomas Jr., Xavier Worthy, Chris Olave, and Others

Take a look at our Week 6 consensus WR fantasy rankings to help with your lineup choices, including start-sit recommendations, waiver wire targets, and trade opportunities.

Week 6 of the fantasy football season has arrived, and it’s more important than ever to know which players deserve a place in your starting lineup. Considering player talent, recent form, and matchups, we’ve put together our PFSN consensus Week 6 WR rankings.

These rankings were last updated at 8:00 AM ET on Monday, October 06, 2025.

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Week 6 WR Fantasy Rankings

1) Puka Nacua | Los Angeles Rams (at BAL)
2) Amon-Ra St. Brown | Detroit Lions (at KC)
3) Jaxon Smith-Njigba | Seattle Seahawks (at JAX)
4) Rome Odunze | Chicago Bears (at WAS)
5) Drake London | Atlanta Falcons (vs. BUF)
6) Emeka Egbuka | Tampa Bay Buccaneers (vs. SF)
7) Garrett Wilson | New York Jets (vs. DEN)
8) George Pickens | Dallas Cowboys (at CAR)
9) Deebo Samuel Sr. | Washington Commanders (vs. CHI)
10) Ja’Marr Chase | Cincinnati Bengals (at GB)
11) Davante Adams | Los Angeles Rams (at BAL)
12) Quentin Johnston | Los Angeles Chargers (at MIA)
13) Xavier Worthy | Kansas City Chiefs (vs. DET)
14) Tetairoa McMillan | Carolina Panthers (vs. DAL)
15) Michael Pittman Jr. | Indianapolis Colts (vs. ARI)
16) Courtland Sutton | Denver Broncos (at NYJ)
17) Jaylen Waddle | Miami Dolphins (vs. LAC)
18) DK Metcalf | Pittsburgh Steelers (vs. CLE)
19) Stefon Diggs | New England Patriots (at NO)
20) Marvin Harrison Jr. | Arizona Cardinals (at IND)
21) Keenan Allen | Los Angeles Chargers (at MIA)
22) Jakobi Meyers | Las Vegas Raiders (vs. TEN)
23) A.J. Brown | Philadelphia Eagles (at NYG)
24) Chris Olave | New Orleans Saints (vs. NE)
25) Ladd McConkey | Los Angeles Chargers (at MIA)
26) Zay Flowers | Baltimore Ravens (vs. LAR)
27) Brian Thomas Jr. | Jacksonville Jaguars (vs. SEA)
28) DeVonta Smith | Philadelphia Eagles (at NYG)
29) Calvin Ridley | Tennessee Titans (at LV)
30) Ricky Pearsall | San Francisco 49ers (at TB)
31) Jameson Williams | Detroit Lions (at KC)
32) Wan’Dale Robinson | New York Giants (vs. PHI)
33) Chris Godwin | Tampa Bay Buccaneers (vs. SF)
34) Tee Higgins | Cincinnati Bengals (at GB)
35) DJ Moore | Chicago Bears (at WAS)
36) Khalil Shakir | Buffalo Bills (at ATL)
37) Cooper Kupp | Seattle Seahawks (at JAX)
38) Rashid Shaheed | New Orleans Saints (vs. NE)
39) Matthew Golden | Green Bay Packers (vs. CIN)
40) Jauan Jennings | San Francisco 49ers (at TB)
41) Kendrick Bourne | San Francisco 49ers (at TB)
42) Romeo Doubs | Green Bay Packers (vs. CIN)
43) Tre Tucker | Las Vegas Raiders (vs. TEN)
44) Josh Downs | Indianapolis Colts (vs. ARI)
45) Keon Coleman | Buffalo Bills (at ATL)
46) Jerry Jeudy | Cleveland Browns (at PIT)
47) Darnell Mooney | Atlanta Falcons (vs. BUF)
48) Troy Franklin | Denver Broncos (at NYJ)
49) Elic Ayomanor | Tennessee Titans (at LV)
50) Hollywood Brown | Kansas City Chiefs (vs. DET)

A.J. Brown, WR, Philadelphia Eagles

When it comes to wide receivers, there aren’t many more talented than Philadelphia Eagles star A.J. Brown. Brown has struggled to get going in fantasy this year and has fallen well short of his WR10 ADP.

In fact, Brown has tallied just one fantasy finish inside the top-35 wide receivers through five weeks. Name-brand will prevent Brown from being traded too cheaply, but current owners are undoubtedly ready to move on if offered reasonable compensation.

The star wide receiver remains an elite talent and could be a league winner down the stretch. Brown has been targeted 35 times in his last four games, which is encouraging. He and teammate Devonta Smith could both have caught a game-winning Hail Mary in Week 5, had they not gotten in each other’s way.

Isaiah Bond, WR, Cleveland Browns

Rookie wide receiver Isaiah Bond was highly rated heading into the NFL Draft, but off-field issues led to him going undrafted. He eventually found a home with the Cleveland Browns and has become a go-to weapon in the passing game.

That hasn’t led to immense production so far, though, and Bond is only 6% rostered in Yahoo leagues, meaning he should be available for free in most leagues. The Browns’ rookie has been targeted 13 times in his last two games, and that volume should result in increased production as Cleveland’s young offense settles.

Bond has stepped into a larger role with Cedric Tillman sidelined, and could easily become a solid flex option in the next week or two.

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