Early Week 5 Fantasy WR Rankings: Start-Sit Advice for Tyreek Hill, Ja’Marr Chase, Jauan Jennings, and Others

Take a look at our Week 5 consensus WR fantasy rankings to help with your lineup choices, including start-sit recommendations, waiver wire targets, and trade opportunities.

Week 5 of the fantasy football season has arrived, and it’s more important than ever to know which players deserve a place in your starting lineup. Considering player talent, recent form, and matchups, we’ve put together our PFSN consensus Week 5 WR rankings.

These rankings were last updated at 11:00 AM ET on Monday, September 29, 2025.

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Week 5 WR Fantasy Rankings

1) Puka Nacua | Los Angeles Rams (vs. SF)
2) Amon-Ra St. Brown | Detroit Lions (at CIN)
3) Jaxon Smith-Njigba | Seattle Seahawks (vs. TB)
4) Garrett Wilson | New York Jets (vs. DAL)
5) Nico Collins | Houston Texans (at BAL)
6) Ja’Marr Chase | Cincinnati Bengals (vs. DET)
7) Justin Jefferson | Minnesota Vikings (vs. CLE (London))
8) George Pickens | Dallas Cowboys (at NYJ)
9) Davante Adams | Los Angeles Rams (vs. SF)
10) Tyreek Hill | Miami Dolphins (at CAR)
11) Zay Flowers | Baltimore Ravens (vs. HOU)
12) Xavier Worthy | Kansas City Chiefs (at JAX)
13) Quentin Johnston | Los Angeles Chargers (vs. WAS)
14) Emeka Egbuka | Tampa Bay Buccaneers (at SEA)
15) Deebo Samuel Sr. | Washington Commanders (at LAC)
16) A.J. Brown | Philadelphia Eagles (vs. DEN)
17) Courtland Sutton | Denver Broncos (at PHI)
18) Tetairoa McMillan | Carolina Panthers (vs. MIA)
19) Michael Pittman Jr. | Indianapolis Colts (vs. LV)
20) Keenan Allen | Los Angeles Chargers (vs. WAS)
21) Chris Olave | New Orleans Saints (vs. NYG)
22) Jakobi Meyers | Las Vegas Raiders (at IND)
23) Marvin Harrison Jr. | Arizona Cardinals (vs. TEN)
24) Chris Godwin | Tampa Bay Buccaneers (at SEA)
25) Jauan Jennings | San Francisco 49ers (at LAR)
26) Brian Thomas Jr. | Jacksonville Jaguars (vs. KC)
27) Ladd McConkey | Los Angeles Chargers (vs. WAS)
28) Jameson Williams | Detroit Lions (at CIN)
29) DeVonta Smith | Philadelphia Eagles (vs. DEN)
30) Tee Higgins | Cincinnati Bengals (vs. DET)
31) Jordan Addison | Minnesota Vikings (vs. CLE (London))
32) Jaylen Waddle | Miami Dolphins (at CAR)
33) Stefon Diggs | New England Patriots (at BUF)
34) Keon Coleman | Buffalo Bills (vs. NE)
35) Calvin Ridley | Tennessee Titans (at ARI)
36) Wan’Dale Robinson | New York Giants (at NO)
37) Khalil Shakir | Buffalo Bills (vs. NE)
38) Jerry Jeudy | Cleveland Browns (vs. MIN (London))
39) Troy Franklin | Denver Broncos (at PHI)
40) Rashid Shaheed | New Orleans Saints (vs. NYG)
41) Elic Ayomanor | Tennessee Titans (at ARI)
42) Travis Hunter | Jacksonville Jaguars (vs. KC)
43) Darius Slayton | New York Giants (at NO)
44) Cooper Kupp | Seattle Seahawks (vs. TB)
45) Christian Kirk | Houston Texans (at BAL)
46) Tre Tucker | Las Vegas Raiders (at IND)
47) Josh Downs | Indianapolis Colts (vs. LV)
48) Kayshon Boutte | New England Patriots (at BUF)
49) Sterling Shepard | Tampa Bay Buccaneers (at SEA)
50) Hollywood Brown | Kansas City Chiefs (at JAX)

Jameson Williams, WR, Detroit Lions

Jameson Williams was tipped by many for a big year in 2025, but has started the season with three fantasy finishes outside the top 50 wide receivers in the opening four weeks. Against Cleveland in Week 4, Williams caught two passes for 40 yards, but he was targeted eight times.

Many of those targets were deep balls and potential walk-in touchdowns, but Jared Goff could not connect. Williams remains a big-play threat, and the Detroit Lions will look to get him going in the coming weeks.

Having started slowly, the Lions have scored 116 points in their last three games, and Williams’s eight targets clearly indicate that Detroit wants him involved. The electric deep threat was the WR22 overall last season and should be available at a huge discount this week.

Jauan Jennings, WR, San Francisco 49ers

Jauan Jennings remains Brock Purdy’s favorite target, but the wide receiver struggled to make an impact in Week 4. The San Francisco 49ers lost 26-21 to the Jacksonville Jaguars, whose defense continues to be underrated.

Jennings was targeted just four times, catching two, having missed Week 3 through injury. Jennings also missed some time in Week 4, having taken a heavy shot to his midsection, but should be good to go for Week 5.

Jennings has posted only one fantasy-relevant week through four weeks, finishing as the WR11 overall in Week 2. The 49ers travel to the Los Angeles Rams in Week 5, where Jennings tallied 175 yards and three touchdowns last season.

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