This year’s Thanksgiving slate ends with an exciting prime-time matchup with the San Francisco 49ers vs. Seattle Seahawks. After a three-game losing streak, the 49ers are back to playing at an elite level and remain undefeated when they’re completely healthy on offense. The Seahawks, meanwhile, have lost two of their three last games but remain firmly in the playoff race.
Before we get into our 49ers vs. Seahawks predictions, let’s take a look at the odds for tonight’s divisional matchup.
San Francisco 49ers vs. Seattle Seahawks Betting Lines
The point spread has moved up from San Francisco -6 since the 49ers vs. Seahawks odds first opened on Sunday night. This is the first time this season that the Seahawks are home underdogs, but they went 3-1 in this spot in 2022. Since the beginning of last season, the 49ers are just 4-7 ATS as a road favorite, according to TeamRankings.
All odds are from FanDuel Sportsbook.
- Spread
49ers -7 - Moneyline
49ers -330, Seahawks +270 - Total
43.5
San Francisco 49ers vs. Seattle Seahawks Predictions
Bearman:Â Crazy to think that we were worried about the 49ers as they entered their bye on a three-game losing streak. Since then, they have smashed Jacksonville and Tampa Bay to re-assert themselves atop of the NFC West and now face their division rival with a banged-up Geno Smith. Smith is more likely to be beaten up after this one with the 49ers defense hunting.
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San Francisco swept this series last year, including in the playoffs. They should be able to cover here.
Pick: 49ers -6.5 (-125 at BetMGM)
Blewis:Â I’ve won a couple of times this season on taking the over on the 49ers’ team total, including last week, and I’m going to run it back tonight.
The over on their team total is 7-0 this season when they’re at full strength. In all seven games with a completely healthy offense, the 49ers scored 27 points or more. With his full set of playmakers, plus Trent Williams at left tackle, Brock Purdy has been crazy efficient this season, and I don’t expect that to change tonight.
Seattle’s defense has mostly feasted on bad offenses, most notably the Giants, Bengals with an injured Joe Burrow, Cardinals, and the P.J. Walker-led Browns. The two only comparable offenses to the 49ers that the Seahawks have faced, the Lions and Ravens, combined for 68 points and 933 yards against them.
Pick: 49ers over 26.5 (+114 at DraftKings)
Soppe:Â Brock Purdy is coming off of a perfect passer rating performance, a game in which he checked every box and was in control throughout. His path to success is quick and accurate decision-making, allowing his elite quartet of playmakers to get the ball in space and make plays.
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It is not to threaten defenses with his legs. If we remove a pair of games against the top two defenses in terms of blitz rate this season, Purdy has given us single-digit rushing totals in six of eight games (one of those outlier performances came in a game with Deebo Samuel sidelined, something that won’t be the case tonight).
The Seahawks rank 24th in blitz rate through 11 weeks and due to my belief that this game could be dominated by the road team, kneel-downs could well work in our favor if this leg of the SGP is in doubt late.
As for the domination of this game, it might be a slow burn. The 49ers rank eighth in average time of possession, while the Seahawks rank 31st. This could be a low-possession game where the Seahawks make a few early stops, but the talent difference figures to win out with time.
This season, six of San Francisco’s seven wins have come by double figures, proving that they can win by margin over four quarters.
Pick: 49ers -7 (-112 at DraftKings)
Katz: I must admit I went back and forth on this for a while before making it an official play. I like Zach Charbonnet a lot as a player. But this is such a high number.
Only three running backs have gone over this number against the 49ers all season. Last week, Charbonnet saw an 85% snap share and played reasonably well but still totaled just 69 yards.
I am not fully fading Charbonnet on Thursday night. I think he will be effective. But he can both play well and not reach 70 total yards. Something like 12 carries for 50 yards, plus three catches for 20 yards and a touchdown mixed in, is a really nice performance. It also still keeps Charbonnet under this number.
Pick: Zach Charbonnet Under 76.5 Rush + Receiving Yards (-115 at DraftKings)
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