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    PFN Insights

    NFL Week 6 Stats and Insights: Fantasy, Betting, and Other Notes For Every Game

    We are onto Week 6 of the NFL season and with that comes the continuation of bye weeks. What does this slate hold for fantasy managers, bettors, and casual fans? Let's dive in!

    Whether you’re setting your fantasy football lineups or you need just a bit more information before getting in on the NFL betting action at your favorite sportsbook, we’ve got you covered here at Pro Football Network with the most important stats, notes, and insights for every NFL matchup in Week 6.

    We all know how time-consuming gathering all the information can be, so we’re doing the research for you so you don’t have to!

    Bye Week Schedule

    • Week 6: Chiefs, Rams, Dolphins, Vikings
    • Week 7: Bears, Cowboys
    • Week 9: Steelers, 49ers
    • Week 10: Browns, Packers, Raiders, Seahawks
    • Week 11: Cardinals, Panthers, Giants, Buccaneers
    • Week 12: Falcons, Bills, Bengals, Jaguars, Saints, Jets
    • Week 14: Ravens, Broncos, Texans, Colts, Patriots, Commanders

    All stats are from TruMedia unless otherwise stated.

    San Francisco 49ers at Seattle Seahawks (TNF)

    San Francisco 49ers

    Team: The Niners have beaten the Seahawks in four straight games, tied for their longest win streak ever vs Seattle (also 4 straight from 2010-12).

    QB: Brock Purdy is averaging a league-high 3.14 seconds to throw, and he’s made lots of big plays on extended dropbacks. On throws taking 3+ seconds, Purdy averages 12.8 yards per attempt and 0.45 EPA per dropback. On throws under 3 seconds, he’s at 6.3 yards per attempt and -0.07 EPA per dropback.

    Offense: The 49ers have the fifth-worst average starting field percentage this season (their own 27.9-yard line). All four teams in the NFC West rank in the bottom 10 through five weeks.

    Defense: The 49ers own the average highest time of possession this season +8:35) by more than two full minutes (second place, Texans: +6:22).

    Fantasy: Purdy is pacing for a very valuable 367 rushing yards this season and faces a Seahawk defense that has allowed the two most viable QBs they faced this season (Jared Goff and Daniel Jones) to complete 41-of-52 passes for 549 yards and four touchdowns.

    Betting: Over tickets have cashed in eight of San Francisco’s last nine road divisional games.

    Seattle Seahawks

    Team: The Seahawks have lost four straight Thursday games, the third-longest active streak behind the Giants (9 straight) and Saints (5).

    QB: Through five weeks, 28 different quarterbacks have thrown multiple touchdown passes in a game – Geno Smith is not on that list.

    Offense: When the game is within one score, the Seahawks have dropped back to pass on 67.2% of their plays, the highest rate in the NFL.

    Defense: It’s inflated by a soft schedule up to this point, but the Seahawks are allowing the seventh-fewest yards per drive this season (they ranked 32nd in 2023).

    Fantasy: Kenneth Walker III had some game script concerns last season (7.6 carries per reception), but he’s seemingly plugged that hole this season (11 catches against 17 carries over the past two weeks).

    Betting: Seattle has only been 3-6 ATS over the past three seasons at home when facing a divisional rival.

    Jacksonville Jaguars vs. Chicago Bears (London)

    Jacksonville Jaguars

    Team: The Jaguars earned their first victory of the season on Sunday (37-34 over the Colts), making this the first time since 2019 that Jacksonville has won its most recent game in the United States before departing for London.

    QB: Trevor Lawrence threw for 371 yards last week against the Colts, the first time he cleared 220 this season. Over his past two games, Lawrence is averaging a touchdown pass once every 16.8 attempts (Weeks 1-3: 44.5).

    Offense: The Jaguars are averaging a league-best 4.2 yards after contact per rush. That’s been a weakness for the Bears defense, which ranks 26th with 3.3 yards after contact allowed per rush.

    Defense: Jacksonville has forced a turnover on just 1.9% of drives, easily the lowest mark in the NFL. Over the past 20 years, the low watermark for turnover rate for an entire season is the 2018 49ers (3.9%).

    Fantasy: Travis Etienne’s next PPR finish inside the top 20 at the position this season will be his first. He was on the field for 72.1% of offensive snaps in Week 3 against the Bills, 51.7% against the Texans in Week 4, and just 38.6% against the Colts on Sunday.

    Betting: Each of Jacksonville’s last four London games has gone under the projected total (5.6 PPG below the closing total) – the Jags have covered three of those contests.

    Chicago Bears

    Team: The Bears are seeking a third straight win. Their last three-game win streak came in Weeks 14-16, 2020 (that means they haven’t strung three wins together since we went to an 18-week schedule).

    QB: Caleb Williams has exactly five rush attempts in four of five games this season and has posted his top-2 PFN QB+ grades in the past two weeks. He gets a favorable matchup this week (JAX: fifth-most yards per pass attempt allowed) before facing the Commanders and Cardinals coming out of his Week 7 bye.

    Offense: The Bears have improved their points per drive with each passing week (0.90, 1.08, 1.33, 2.40, and 3.00 last weekend against the Panthers).

    Defense: The Bears have the best defensive EPA per dropback this season (0.28). It’s Chicago’s best defensive EPA per dropback since at least 2000.

    Fantasy: D’Andre Swift’s snap share isn’t budging (exactly two-thirds in three of his past four games), but he has posted consecutive top-5 PPR weeks at the position and faces the third-worst red zone defense in the league up to this point.

    Betting: The Bears have covered four straight games as a favorite, the longest active streak in the NFL. Another cover would tie their longest streak since 2000 (five straight in 2018 and 2005-06).

    Arizona Cardinals at Green Bay Packers

    Arizona Cardinals

    Team: All-or-nothing in terms of competition. The Cardinals have played three games, which were decided by seven or fewer points (24-23 win last week in San Francisco), and two games were decided by at least 28 points this season.

    QB: Kyler Murray owns an 86.4 Passer Rating in the pocket this season, pacing him for a third straight season of decline.

    Offense: The Cardinals (1.80) are the only NFL team through five weeks committing fewer than two offensive penalties per game.

    Defense: Arizona is allowed the third most yards per drive this season (36.4 yards).

    Fantasy: James Conner was one of the most efficient fantasy RBs a season ago and has opened 2024 with four top-20 finishes in five weeks. Are the Packers, the fourth worst run defense in terms of yards per carry allowed to running backs after carry, the team that will stop that trend?

    Betting: Kyler Murray has covered 18-of-24 (75%) of his career road games when playing outside of the NFC West.