College Football Predictions Week 10: Projecting Every Game, Headlined by a Big 12 Battle

Before the season, it was dubbed as the best Saturday of the year, and our college football predictions have the score for every Week 10 showdown.

Our college football predictions for Week 10, compiled using the PFSN College Football Playoff Predictor, provide the answer to the question of who is winning in a packed slate of games! Don’t like these results? You can predict a conference, every game, or simulate the entire season to discover which 12 teams will make the College Football Playoff. Get started right now!

PFSN 2026-2027 CFB Playoff Predictor
Play out the entire college football season with PFSN's CFB Playoff Predictor to see what it means for conference standings and the CFB playoffs!

Penn State vs. Ohio State Prediction

  • Prediction: Penn State 14, Ohio State 24
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: FOX

Vanderbilt vs. Texas Prediction

  • Prediction: Vanderbilt 30, Texas 17
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: ABC

Miami (FL) vs. SMU Prediction

  • Prediction: Miami (FL) 37, SMU 27
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: ESPN

West Virginia vs. Houston Prediction

  • Prediction: West Virginia 23, Houston 35
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: FS1

Rutgers vs. Illinois Prediction

  • Prediction: Rutgers 14, Illinois 27
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: NBC

Duke vs. Clemson Prediction

  • Prediction: Duke 33, Clemson 21
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: ACC Network

UCF vs. Baylor Prediction

  • Prediction: UCF 17, Baylor 27
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: ESPNU

UAB vs. UConn Prediction

  • Prediction: UAB 27, UConn 40
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: CBSSN

Army vs. Air Force Prediction

  • Prediction: Army 30, Air Force 13
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: CBS

Navy vs. North Texas Prediction

  • Prediction: Navy 33, North Texas 30
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: ESPN2

Buffalo vs. Bowling Green Prediction

  • Prediction: Buffalo 23, Bowling Green 35
  • Date: Saturday, Nov. 1, Noon ET
  • TV Channel: ESPN+

Arizona State vs. Iowa State Prediction

  • Prediction: Arizona State 13, Iowa State 30
  • Date: Saturday, Nov. 1, 1 p.m. ET
  • TV Channel: TNT

East Carolina vs. Temple Prediction

  • Prediction: East Carolina 38, Temple 24
  • Date: Saturday, Nov. 1, 2 p.m. ET
  • TV Channel: ESPN+

Louisville vs. Virginia Tech Prediction

  • Prediction: Louisville 27, Virginia Tech 14
  • Date: Saturday, Nov. 1, 3 p.m. ET
  • TV Channel: The CW Network

New Mexico vs. UNLV Prediction

  • Prediction: New Mexico 27, UNLV 40
  • Date: Saturday, Nov. 1, 3 p.m. ET
  • TV Channel:

Indiana vs. Maryland Prediction

  • Prediction: Indiana 30, Maryland 17
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: CBS

Georgia vs. Florida Prediction

  • Prediction: Georgia 27, Florida 17
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: ABC

Notre Dame vs. Boston College Prediction

  • Prediction: Notre Dame 40, Boston College 27
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: ESPN

Texas Tech vs. Kansas State Prediction

  • Prediction: Texas Tech 30, Kansas State 17
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: FOX

Michigan State vs. Minnesota Prediction

  • Prediction: Michigan State 27, Minnesota 40
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: BTN

Pittsburgh vs. Stanford Prediction

  • Prediction: Pittsburgh 33, Stanford 21
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: ACC Network

Delaware vs. Liberty Prediction

  • Prediction: Delaware 27, Liberty 10
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: CBSSN

New Mexico State vs. Western Kentucky Prediction

  • Prediction: New Mexico State 14, Western Kentucky 30
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: ESPN+

Fresno State vs. Boise State Prediction

  • Prediction: Fresno State 13, Boise State 27
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: FS1

Old Dominion vs. Louisiana-Monroe Prediction

  • Prediction: Old Dominion 24, Louisiana-Monroe 10
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: ESPN+

Louisiana vs. South Alabama Prediction

  • Prediction: Louisiana 21, South Alabama 31
  • Date: Saturday, Nov. 1, 3:30 p.m. ET
  • TV Channel: ESPN+

Virginia vs. California Prediction

  • Prediction: Virginia 14, California 33
  • Date: Saturday, Nov. 1, 3:45 p.m. ET
  • TV Channel: ESPN2

Mississippi State vs. Arkansas Prediction

  • Prediction: Mississippi State 30, Arkansas 10
  • Date: Saturday, Nov. 1, 4 p.m. ET
  • TV Channel: SEC Network

Oklahoma State vs. Kansas Prediction

  • Prediction: Oklahoma State 10, Kansas 27
  • Date: Saturday, Nov. 1, 4 p.m. ET
  • TV Channel: ESPN+

Central Michigan vs. Western Michigan Prediction

  • Prediction: Central Michigan 24, Western Michigan 10
  • Date: Saturday, Nov. 1, 4 p.m. ET
  • TV Channel: ESPNU

South Carolina vs. Ole Miss Prediction

  • Prediction: South Carolina 14, Ole Miss 30
  • Date: Saturday, Nov. 1, 7 p.m. ET
  • TV Channel: ESPN

Purdue vs. Michigan Prediction

  • Prediction: Purdue 30, Michigan 35
  • Date: Saturday, Nov. 1, 7 p.m. ET
  • TV Channel: BTN

Arizona vs. Colorado Prediction

  • Prediction: Arizona 37, Colorado 35
  • Date: Saturday, Nov. 1, 7 p.m. ET
  • TV Channel: FS1

Wyoming vs. San Diego State Prediction

  • Prediction: Wyoming 13, San Diego State 31
  • Date: Saturday, Nov. 1, 7 p.m. ET
  • TV Channel: CBSSN

Georgia Tech vs. NC State Prediction

  • Prediction: Georgia Tech 27, NC State 10
  • Date: Saturday, Nov. 1, 7:30 p.m. ET
  • TV Channel: ESPN2

Oklahoma vs. Tennessee Prediction

  • Prediction: Oklahoma 34, Tennessee 17
  • Date: Saturday, Nov. 1, 7:30 p.m. ET
  • TV Channel: ABC

USC vs. Nebraska Prediction

  • Prediction: USC 33, Nebraska 30
  • Date: Saturday, Nov. 1, 7:30 p.m. ET
  • TV Channel: NBC

Kentucky vs. Auburn Prediction

  • Prediction: Kentucky 21, Auburn 37
  • Date: Saturday, Nov. 1, 7:30 p.m. ET
  • TV Channel: SEC Network

Washington State vs. Oregon State Prediction

  • Prediction: Washington State 24, Oregon State 21
  • Date: Saturday, Nov. 1, 7:30 p.m. ET
  • TV Channel: CBS

Wake Forest vs. Florida State Prediction

  • Prediction: Wake Forest 37, Florida State 31
  • Date: Saturday, Nov. 1, 7:30 p.m. ET
  • TV Channel: ACC Network

Arkansas State vs. Troy Prediction

  • Prediction: Arkansas State 17, Troy 33
  • Date: Saturday, Nov. 1, 8 p.m. ET
  • TV Channel: ESPNU

Cincinnati vs. Utah Prediction

  • Prediction: Cincinnati 31, Utah 34
  • Date: Saturday, Nov. 1, 10:15 p.m. ET
  • TV Channel: ESPN

Hawai’i vs. San José State Prediction

  • Prediction: Hawaii 31, San Jose State 17
  • Date: Saturday, Nov. 1, 10:30 p.m. ET
  • TV Channel: CBSSN

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