The Kansas City Chiefs will visit the Tennessee Titans in Week 16. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, specifically regarding QB Patrick Mahomes.
Is Patrick Mahomes Playing in Week 16?
Mahomes has begun rehab following surgery to repair the torn ACL and LCL in his left knee, and the Chiefs are optimistic that the star quarterback could be back as soon as Week 1 of the 2026 regular season, ESPN.com reports.
We’ll continue to monitor the Chiefs’ injury report leading up to kickoff for any changes. You can also visit and bookmark our Fantasy News Tracker for the latest updates.
Should You Start or Sit Mahomes in Week 16?
By now, you’re well aware of what happened to Patrick Mahomes over the weekend.
A torn ACL ended his season shortly before the playoff hopes for the Chiefs were dashed, and now he’s gearing up for a recovery process that could butt up against the start of the 2026 regular season.
We can jump into his future evaluation as he progresses through rehab, and this roster comes into focus, but it’s plenty fair to ask questions. Mahomes scored 25.3% of his fantasy points in 2025 with his legs, easily topping the career high that he set in 2024 of 15.1%.
Does this injury change how he plays?
Does this offense add weapons to adjust to any tweaks in his style?
How favorable a schedule do the Chiefs get with a third-place finish?
There are a lot of things to sort out in the profile between now and your draft. There’s a natural urge to form opinions now, but I encourage you to wait and gather facts as they become available over the next few months.
Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.
Mahomes’ Fantasy Points Projection in Week 16
Mahomes is projected to score 0.0 points in PPR formats. This includes 0.0 receptions for 0.0 yards and 0.0 touchdowns.
Check out the free PFSN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.
Week 16 Weather Impact: Chiefs at Titans
The forecast for kickoff is 54 degrees Fahrenheit with 10 mph winds. These are ideal conditions for fantasy production.
