The Los Angeles Rams comfortably defeated the San Francisco 49ers with a dominant offensive performance, putting up 42 points and taking full advantage of San Francisco’s depleted defense behind a standout game from Matthew Stafford.
Here are four things you need to know about the Rams’ Week 10 victory over the 49ers:
1. San Francisco Defense Will Be a Liability Moving Forward
Before the season began, questions arose about the quality of the 49ers’ roster, considered one of the weakest since Kyle Shanahan took over the franchise. For a team already short on elite talent, losing Fred Warner, Nick Bosa, and rookie Mykel Williams for the season is a price they simply cannot afford.
Stafford was sacked only once, with Kalia Davis and Keion White sharing the sack on a single play. The Rams quarterback had all the time he needed to make his throws and once again delivered a strong performance.
When San Francisco faces more capable offenses, the defense will struggle. Even though Tatum Bethune did a respectable job in Warner’s absence and Bryce Huff managed to generate some pressure, neither player can replicate what Warner and Bosa bring to the team.
2. Matthew Stafford Is the MVP Frontrunner
The MVP race this season will be incredibly difficult to predict. Jaxon Smith-Njigba has already surpassed 1,000 receiving yards, while Jonathan Taylor has topped 1,000 rushing yards and reached 17 total touchdowns. Still, the impact of the quarterback position cannot be overlooked.
Walks it in for the 40-piece!
📺 @NFLonFOX | #RamsHouse pic.twitter.com/Ug8ukkXW4w
— Los Angeles Rams (@RamsNFL) November 10, 2025
With Sunday’s game, Stafford reached 25 passing touchdowns on the year with only two interceptions, the last of which came in Week 3 against the Philadelphia Eagles. He also has at least four touchdowns in each of the last three games.
No quarterback has been as efficient as Stafford, who has complete command of the Los Angeles offense, shining with play-action and targeting his tight ends against San Francisco. He completed 24 of 26 passes for 280 yards and four touchdowns, once again proving why the team remains a Super Bowl contender under his leadership.
3. Brian Robinson Needs To Get More Touches
No one can take away from what Christian McCaffrey has done for the 49ers this season. He entered Week 10 leading the NFL in scrimmage yards and remains a key reason San Francisco is still in playoff contention despite numerous injuries. However, the backfield needs to be more balanced.
Robinson finished the game with eight carries for 41 yards, averaging 5.1 yards per attempt and scoring a touchdown, while McCaffrey managed just 30 rushing yards on 12 carries, averaging only 2.5 yards per attempt. Through the air, McCaffrey added 66 receiving yards on eight catches.
Brian Robinson Jr. breaks the tackle and finds pay dirt!
LARvsSF on FOX/FOX Onehttps://t.co/HkKw7uXVnt pic.twitter.com/2UB6BUf6rS
— NFL (@NFL) November 9, 2025
While McCaffrey remains the 49ers’ most important playmaker alongside George Kittle, he does not have the physical power Robinson brings when running behind this San Francisco offensive line, which often allows penetration and early contact. Robinson deserves more opportunities for the ground game to find its rhythm.
4. San Francisco Is The Third-Best Team in the Division
It’s hard to argue otherwise when looking at the recent performances of the Seattle Seahawks and the Rams. Both offenses appear unstoppable, as the 49ers saw firsthand on Sunday afternoon. Seattle has scored at least 35 points before halftime in each of the past two weeks and has been one of the most explosive teams in the league.
Meanwhile, the 49ers look like a team fighting week to week just to stay afloat as they work to get playmakers like Ricky Pearsall and Brandon Aiyuk back, along with Brock Purdy, whose return from a turf-toe injury remains uncertain.
It feels like one of those seasons where nothing has gone right for San Francisco, though credit the team for still being in playoff contention and finding ways to win when possible. The 49ers’ fight now seems less about chasing the NFC West title and more about battling for a Wild Card spot in the NFC.
