College Football Predictions Week 4: Projecting Every Single Game Including Auburn vs. Oklahoma

College football Week 4 got off to a bang with Scott Abell’s Rice Owls looking good, the Iowa Hawkeyes running Rutgers into the ground, and the Tulsa Golden Hurricanes burying Mike Gundy and the Oklahoma State Cowboys. Now, attention turns to a packed Saturday slate, but who’s winning this weekend?

Our college football predictions for Week 4, compiled using the PFSN College Football Playoff Predictor, seek to answer that question and more! Predict a conference, predict every game, or simulate the entire season to discover which 12 teams will make the 2025-2026 College Football Playoff. Get started right now!

Syracuse vs. Clemson Prediction

• Prediction: Syracuse 40, Clemson 37
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: ESPN

Wofford vs. Virginia Tech Prediction

• Prediction: Wofford 10, Virginia Tech 37
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: ESPN+

Texas Tech vs. Utah Prediction

• Prediction: Texas Tech 21, Utah 35
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: FOX

Arkansas vs. Memphis Prediction

• Prediction: Arkansas 34, Memphis 21
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: ABC

Maryland vs. Wisconsin Prediction

• Prediction: Maryland 27, Wisconsin 10
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: Big Ten Network

SMU vs. TCU Prediction

• Prediction: SMU 14, TCU 31
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: ESPN

Bowling Green vs. Louisville Prediction

• Prediction: Bowling Green 21, Louisville 33
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: ACC Network

UNLV vs. Miami (Ohio) Prediction

• Prediction: UNLV 27, Miami (OH) 17
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: ESPNU

North Texas vs. Army Prediction

• Prediction: North Texas 23, Army 13
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: CBSSN

South Carolina State vs. South Florida Prediction

• Prediction: South Carolina State 17, South Florida 34
• Date: Saturday, Sept. 20, 12:00 p.m. ET
• TV Channel: ESPN+

UAB vs. Tennessee Prediction

• Prediction: UAB 21, Tennessee 40
• Date: Saturday, Sept. 20, 12:45 p.m. ET
• TV Channel: SEC Network

Wagner vs. Central Michigan Prediction

• Prediction: Wagner 21, Central Michigan 35
• Date: Saturday, Sept. 20, 1 p.m. ET
• TV Channel: ESPN+

Oregon State vs. Oregon Prediction

• Prediction: Oregon State 23, Oregon 37
• Date: Saturday, Sept. 20, 3:00 p.m. ET
• TV Channel: Big Ten Network

Purdue vs. Notre Dame Prediction

• Prediction: Purdue 17, Notre Dame 33
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: NBC/Peacock

Kent State vs. Florida State Prediction

• Prediction: Kent State 10, Florida State 21
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: ACC Network

Auburn vs. Oklahoma Prediction

• Prediction: Auburn 17, Oklahoma 34
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: ABC

Tulane vs. Ole Miss Prediction

• Prediction: Tulane 21, Ole Miss 31
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: ESPN

Michigan vs. Nebraska Prediction

• Prediction: Michigan 33, Nebraska 21
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: CBS/Paramount+

North Carolina vs. UCF Prediction

• Prediction: North Carolina 24, UCF 13
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: FOX

Ball State vs. UConn Prediction

• Prediction: Ball State 10, UConn 30
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: CBSSN

James Madison vs. Liberty Prediction

• Prediction: James Madison 37, Liberty 27
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: ESPNU

Louisiana vs. Eastern Michigan Prediction

• Prediction: Louisiana 13, Eastern Michigan 21
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: ESPN+

Troy vs. Buffalo Prediction

• Prediction: Troy 24, Buffalo 35
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: ESPN+

Toledo vs. Western Michigan Prediction

• Prediction: Toledo 17, Western Michigan 14
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: ESPN+

Gardner-Webb vs. Ohio Prediction

• Prediction: Gardner-Webb 10, Ohio 30
• Date: Saturday, Sept. 20, 3:30 p.m. ET
• TV Channel: ESPN+

NC State vs. Duke Prediction

• Prediction: NC State 40, Duke 31
• Date: Saturday, Sept. 20, 4:00 p.m. ET
• TV Channel: ESPN2

Northern Illinois vs. Mississippi State Prediction

• Prediction: Northern Illinois 17, Mississippi State 37
• Date: Saturday, Sept. 20, 4:15 p.m. ET
• TV Channel: SEC Network

Temple vs. Georgia Tech Prediction

• Prediction: Temple 17, Georgia Tech 30
• Date: Saturday, Sept. 20, 4:30 p.m. ET
• TV Channel: The CW Network

Idaho vs. San Jose State Prediction

• Prediction: Idaho 10, San Jose State 21
• Date: Saturday, Sept. 20, 5 p.m. ET
• TV Channel: Mountain West Network

West Virginia vs. Kansas Prediction

• Prediction: West Virginia 17, Kansas 33
• Date: Saturday, Sept. 20, 6:00 p.m. ET
• TV Channel: FS1

Delaware vs. Florida International Prediction

• Prediction: Delaware 37, Florida International 34
• Date: Saturday, Sept. 20, 6:00 p.m. ET
• TV Channel: ESPN+

Arkansas State vs. Kennesaw State Prediction

• Prediction: Arkansas State 34, Kennesaw State 17
• Date: Saturday, Sept. 20, 6:00 p.m. ET
• TV Channel: ESPN+

Duquesne vs. Akron Prediction

• Prediction: Duquesne 27, Akron 37
• Date: Saturday, Sept. 20, 6:00 p.m. ET
• TV Channel: ESPN+

South Carolina vs. Missouri Prediction

• Prediction: South Carolina 34, Missouri 14
• Date: Saturday, Sept. 20, 7:00 p.m. ET
• TV Channel: ESPN

Marshall vs. Middle Tennessee Prediction

• Prediction: Marshall 10, Middle Tennessee 24
• Date: Saturday, Sept. 20, 7:00 p.m. ET
• TV Channel: ESPN+

Murray State vs. Jacksonville State Prediction

• Prediction: Murray State 21, Jacksonville State 37
• Date: Saturday, Sept. 20, 7:00 p.m. ET
• TV Channel: ESPN+

UT Martin vs. Missouri State Prediction

• Prediction: UT Martin 10, Missouri State 24
• Date: Saturday, Sept. 20, 7:00 p.m. ET
• TV Channel: ESPN+

Nevada vs. Western Kentucky Prediction

• Prediction: Nevada 24, Western Kentucky 35
• Date: Saturday, Sept. 20, 7:00 p.m. ET
• TV Channel: ESPN+

Boise State vs. Air Force Prediction

• Prediction: Boise State 40, Air Force 21
• Date: Saturday, Sept. 20, 7:00 p.m. ET
• TV Channel: CBSSN

Maine vs. Georgia Southern Prediction

• Prediction: Maine 20, Georgia Southern 37
• Date: Saturday, Sept. 20, 7:00 p.m. ET
• TV Channel: CBSSN

Coastal Carolina vs. South Alabama Prediction

• Prediction: Coastal Carolina 21, South Alabama 35
• Date: Saturday, Sept. 20, 7:00 p.m. ET
• TV Channel: ESPN+

Florida vs. Miami (FL) Prediction

• Prediction: Florida 21, Miami (FL) 37
• Date: Saturday, Sept. 20, 7:30 p.m. ET
• TV Channel: The CW Network

Illinois vs. Indiana Prediction

• Prediction: Illinois 21, Indiana 30
• Date: Saturday, Sept. 20, 7:30 p.m. ET
• TV Channel: NBC

Georgia State vs. Vanderbilt Prediction

• Prediction: Georgia State 10, Vanderbilt 27
• Date: Saturday, Sept. 20, 7:30 p.m. ET
• TV Channel: ESPNU

Arizona State vs. Baylor Prediction

• Prediction: Arizona State 34, Baylor 21
• Date: Saturday, Sept. 20, 7:30 p.m. ET
• TV Channel: FOX

Washington vs. Washington State Prediction

• Prediction: Washington 24, Washington State 10
• Date: Saturday, Sept. 20, 7:30 p.m. ET
• TV Channel: CBS

Stanford vs. Virginia Prediction

• Prediction: Stanford 21, Virginia 40
• Date: Saturday, Sept. 20, 7:30 p.m. ET
• TV Channel: ACC Network

BYU vs. East Carolina Prediction

• Prediction: BYU 37, East Carolina 17
• Date: Saturday, Sept. 20, 7:30 p.m. ET
• TV Channel: ESPN2

Southern Miss vs. Louisiana Tech Prediction

• Prediction: Southern Miss 30, Louisiana Tech 10
• Date: Saturday, Sept. 20, 7:30 p.m. ET
• TV Channel: ESPN+

SE Louisiana vs. LSU Prediction

• Prediction: SE Louisiana 17, LSU 31
• Date: Saturday, Sept. 20, 7:45 p.m. ET
• TV Channel: SEC Network

Sam Houston vs. Texas Prediction

• Prediction: Sam Houston 21, Texas 40
• Date: Saturday, Sept. 20, 8:00 p.m. ET
• TV Channel: ESPN+/SECN+

McNeese vs. Utah State Prediction

• Prediction: McNeese 20, Utah State 33
• Date: Saturday, Sept. 20, 8:00 p.m. ET
• TV Channel: ESPN+/SECN+

Nicholls vs. Texas State Prediction

• Prediction: Nicholls 10, Texas State 24
• Date: Saturday, Sept. 20, 8:00 p.m. ET
• TV Channel: ESPN+/SECN+

Louisiana-Monroe vs. UTEP Prediction

• Prediction: Louisiana-Monroe 14, UTEP 30
• Date: Saturday, Sept. 20, 9:00 p.m. ET
• TV Channel: ESPN+

UTSA vs. Colorado State Prediction

• Prediction: UTSA 35, Colorado State 21
• Date: Saturday, Sept. 20, 9:30 p.m. ET
• TV Channel: FS1

Wyoming vs. Colorado Prediction

• Prediction: Wyoming 21, Colorado 27
• Date: Saturday, Sept. 20, 10:15 p.m. ET
• TV Channel: ESPN

California vs. San Diego State Prediction

• Prediction: California 31, San Diego State 17
• Date: Saturday, Sept. 20, 10:30 p.m. ET
• TV Channel: CBSSN

Michigan State vs. USC Prediction

• Prediction: Michigan State 10, USC 23
• Date: Saturday, Sept. 20, 11:00 p.m. ET
• TV Channel: FOX

Fresno State vs. Hawai’i Prediction

• Prediction: Fresno State 35, Hawaii 31
• Date: Saturday, Sept. 20, 11:59 p.m. ET
• TV Channel: Spectrum Sports