Should You Start Los Angeles Chargers RBs Omarion Hampton or Najee Harris in Fantasy Football Week 2?

Omarion Hampton was the clear Chargers RB1 last week, but the fantasy production didn't follow. Could we see more Najee Harris in Week 2?

The Los Angeles Chargers’ backfield hierarchy became clear after their Week 1 victory over Kansas City — Omarion Hampton and Najee Harris did not exactly split duties.

It was pretty much all Hampton. However, the fantasy football production did not follow. Can managers trust the Chargers’ rookie in Week 2 lineups?

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Omarion Hampton Fantasy Outlook

Week 1 was very much an eye-of-the-beholder type performance for Hampton, where it’s very easy to see what you want to see depending on your preconceived notions.

If you’re a Hampton detractor, you would point to his dismal 15 carries for 48 yards, a concerning 3.2 yards per carry average that suggests inefficiency. The limited explosiveness on the ground could be viewed as a red flag for future production.

Hampton critics would also note that this was Harris’s first real action in nearly two months due to his eye injury recovery, and the veteran is likely to see increased work moving forward as he returns to full health.

However, if you’re a Hampton supporter, you would remind the opposition that this was the rookie’s first career regular-season game, and the usage was absolutely incredible. Hampton played 52 snaps, the most by an NFL rookie running back in Week 1 since Harris himself had 58 snaps with Pittsburgh in 2021.

Hampton’s 94% opportunity share was remarkable when excluding quarterback and wide receiver rushes, demonstrating the Chargers’ complete trust in their first-round investment. He handled 15 carries while adding two receptions for 13 yards, totaling 17 touches in his NFL debut.

The performance also came against the Chiefs’ elite run defense, which ranked No. 1 against the position in 2024, allowing just 108.1 rushing yards per game. Facing such a formidable defensive front in his first game provides context for the efficiency concerns while highlighting the volume commitment from the coaching staff.

Najee Harris Fantasy Outlook

Let’s not bury the lede here — no one is starting Harris in Week 2. This discussion is more about Hampton’s outlook than any realistic fantasy consideration for the veteran back. Harris played just 12 snaps while handling only two total touches (one carry for five yards, one reception for five yards).

Harris is the veteran presence and will undoubtedly have a larger role going forward as he continues recovering from his eye injury and builds back into game shape. However, it’s clear that this is Hampton’s backfield based on the Week 1 usage patterns and long-term organizational investment.

RELATED: Week 2 Fantasy RB Cut List Includes Kaleb Johnson, Jerome Ford, and Najee Harris

The rookie out-touched the former Pittsburgh Steeler 17-2 in the opener, with Hampton receiving both the start and the overwhelming majority of opportunities throughout the contest.

HC Jim Harbaugh indicated before the game that Harris would play 12-15 snaps, and he ended up with exactly 12, suggesting the usage was planned rather than performance-based.

Harris functions as nothing more than a handcuff at this point in the season, though that could evolve as he gets healthier and more acclimated to the system. For Week 2 purposes, he’s purely a bench stash for Hampton managers or deep league considerations.

Should You Start Hampton or Harris This Week?

The matchup against Las Vegas presents a more favorable environment for the Chargers’ ground game than they faced in Week 1. The Raiders ranked 17th against the run last season, allowing 116.9 rushing yards per game, which suggests an average run defense that shouldn’t dramatically move the needle in either direction.

Therefore, Las Vegas being the opponent should not significantly influence decision-making processes. Fantasy managers should play the guys they think can produce based on role and opportunity rather than getting caught up in perceived matchup advantages that may prove minimal.

MORE: Free Fantasy Football Start/Sit Optimizer

The Chargers should be able to run the ball more effectively this week against a less imposing defensive front than Kansas City’s elite unit. If Los Angeles can establish their preferred ground game and reach scoring position, it’s reasonable to assume Hampton will be the one punching in short touchdowns near the goal line.

Fantasy managers drafted Hampton in the third round with expectations of immediate production and workhorse usage. Despite the concerning efficiency in his debut, benching a first-round NFL draft pick who received 94% of the backfield opportunities would be a premature overreaction to small sample size concerns.

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