Oregon vs. Ohio State odds, prediction, how to watch in Week 2

Oregon vs. Ohio State is a game that many anticipated -- odds, predictions, and how to watch the Big Ten/Pac-12 showdown in Week 2.

If you came into the college football season excited for Oregon vs. Ohio State, your expectations lessened a little after Week 1. Still, it’s a ranked matchup that features a ton of NFL talent. Both teams rolled out new quarterbacks in those games, but now they face their teams’ biggest game of the season. Let’s dive into Oregon vs. Ohio State and analyze the odds, make predictions, and reveal how to watch the Big Ten/Pac-12 showdown in Week 2.

Oregon vs. Ohio State | Week 2 preview and prediction

Let’s get the obvious out of the way first. The Oregon Ducks must find a way to slow down Chris Olave and Garrett Wilson. Ohio State’s duo combined for 197 yards and 3 touchdowns last week, but it comes down to C.J. Stroud getting them the ball.

Oregon pass rusher Kayvon Thibodeaux will be the focus of impeding Stroud’s success. If he’s in the young quarterback’s face a lot, Stroud struggles. If not, Olave and Wilson eat. Ryan Day knows he must find ways to chip Thibodeaux or send extra blockers his way to give Stroud more time, but he knows the Oregon star can only be subdued for so long.

Mario Cristobal has his own quarterback to protect, but he saw that his team supports their poised quarterback Anthony Brown. Ohio State boasts a dangerous defensive line that can get in Brown’s face, and it’s up to the Ducks’ offensive line to make sure they’re up for the challenge. After all, a College Football Playoff appearance is on the line for both teams this season.

Oregon’s trying to get back to the postseason tournament for the first time since 2014, and they’ll do things a little differently than that team. While Oregon has the potential to be explosive offensively, it’s the defense that will lead the way. A relatively inexperienced secondary needs to step up. However, Thibodeaux and star linebacker Noah Sewell provide leadership and high-ceiling play. That’s huge when they play a team like Ohio State.

Ohio State’s struggles against Minnesota provided them with learning opportunities. Oregon squeaked out a win over Fresno State but received a chance to play in the clutch against a good team. Something’s got to give, and it comes down to who learned and adjusted the most from Week 1.

How to watch Oregon vs. Ohio State

  • Location: Ohio Stadium, Columbus, OH
  • Start time: 12 PM ET
  • TV channel: FOX
  • Live stream:
    • SlingTV
    • YouTubeTV

Odds for Oregon vs. Ohio State

  • Spread: Ohio State -14.5
  • Moneyline: Oregon +450, Ohio State -700
  • Over/Under: 64

Oregon goes from a 19-point favorite against Fresno State to a 14.5-point underdog in one week. Ohio State, meanwhile, is nearly the same as it was last week when it was a 14-point favorite over Minnesota.