NFL Week 13 Odds and Betting Trends Against the Spread: Dak Prescott, Patrick Mahomes, and Trevor Lawrence All on Prime Time

With six teams on bye and the injuries piling up, the NFL Week 13 odds board is rather unique. Which direction do the trends point?

We have three months of data at our disposal — our feel for these teams is improving, but that also means sharp NFL Week 13 betting lines from the bookmakers. That said, there are some interesting trends developing in specific spots that can help guide you in building out the NFL betting card this week.

NFL Week 13 Odds and Betting Trends

All odds are from ESPN BET, and betting trends are from Inside Edge.

Seattle Seahawks vs. Dallas Cowboys Odds

    • Spread
      Cowboys -9
    • Moneyline
      Seahawks +340, Cowboys -425
    • Total
      46.5

Unders are 9-15-1 in the past 25 games that have featured the Seattle Seahawks as an underdog.

Since the beginning of last season, overs are 12-5 following a Dallas Cowboys win (70.6%, fourth highest).

Indianapolis Colts vs. Tennessee Titans Odds

    • Spread
      Colts -2
    • Moneyline
      Colts -125, Titans +105
    • Total
      43.5

The Indianapolis Colts are the third-worst ATS team in divisional games since the beginning of 2021 (5-11).

MORE: Early Week 13 Prediction, ATS Picks

The Tennessee Titans have covered 60% of their games as an underdog since 2021 (seventh highest rate), while the Colts are a sub-.500 ATS team when favored over that stretch (8-10).

Los Angeles Chargers vs. New England Patriots Odds

    • Spread
      Chargers -6
    • Moneyline
      Chargers -270, Patriots +220
    • Total
      39.5

The Los Angeles Chargers have covered six of their past seven games against bottom-10 offenses.

Since 2021, the New England Patriots are 1-7 outright (2-6 ATS) when getting points at home.

Detroit Lions vs. New Orleans Saints Odds

    • Spread
      Lions -4
    • Moneyline
      Lions -200, Saints +170
    • Total
      45.5

Since 2021, the Detroit Lions have been the best ATS team in the league (30-15), while only the Chicago Bears and Carolina Panthers have been worse than the New Orleans Saints (18-26-1).

Unders are 9-3 since the beginning of last season when the Saints are an underdog.

Atlanta Falcons vs. New York Jets Odds

    • Spread
      Falcons -3
    • Moneyline
      Falcons -150, Jets +130
    • Total
      33.5

The Atlanta Falcons have covered just three of 12 games when favored since the beginning of last season.

Unders are 10-4 since the beginning of last season when the New York Jets play at home (second highest rate).

Arizona Cardinals vs. Pittsburgh Steelers Odds

    • Spread
      Steelers -5.5
    • Moneyline
      Cardinals +210, Steelers -250
    • Total
      39.5

Only the Cincinnati Bengals have been better ATS since 2021 when playing non-divisional games than the Arizona Cardinals (19-11).

MORE: PFN’s FREE NFL Playoff Predictor

The Pittsburgh Steelers have covered seven of 10 games when favored since the beginning of last season.

Miami Dolphins vs. Washington Commanders Odds

    • Spread
      Dolphins -9.5
    • Moneyline
      Dolphins -450, Commanders +360
    • Total
      50.5

The Washington Commanders are among the league leaders in pass rate over expectation, and the Miami Dolphins have seen six of their past nine games against top-10 passing offenses go under the projected total.

Unders are 10-3 since the start of 2021 when the Commanders are a home underdog (76.9%, fifth highest).

Denver Broncos vs. Houston Texans Odds

    • Spread
      Texans -3.5
    • Moneyline
      Broncos +155, Texans -185
    • Total
      46.5

Under tickets have chased in nine of the Denver Broncos’ past 13 games as an underdog.

Unders are 9-5 since the beginning of last season when the Houston Texans play at home.

Carolina Panthers vs. Tampa Bay Buccaneers Odds

    • Spread
      Buccaneers -5.5
    • Moneyline
      Panthers +200, Buccaneers -240
    • Total
      37.5

The Panthers are the worst ATS team since the beginning of last season when coming off of a loss (9-19-2).

Unders are 13-4 in the past 17 games in which the Tampa Bay Buccaneers have been favored.

Cleveland Browns vs. Los Angeles Rams Odds

    • Spread
      Rams -4
    • Moneyline
      Browns +175, Rams -210
    • Total
      39.5

Overs are 8-5 when the Cleveland Browns play on the road since the beginning of last season (third-highest hit rate).

Overs are 5-3 since the beginning of last season when the Los Angeles Rams played a top-10 defense.

San Francisco 49ers vs. Philadelphia Eagles Odds

    • Spread
      49ers -2.5
    • Moneyline
      49ers -145, Eagles +125
    • Total
      46.5

The San Francisco 49ers are the second-best ATS team following a win since the beginning of last season (12-5).

MORE: NFC Conference Round Rematch Odds

Overs are 13-7 following a Philadelphia Eagles win since the beginning of last season.

Kansas City Chiefs vs. Green Bay Packers Odds

    • Spread
      Chiefs -6.5
    • Moneyline
      Chiefs -290, Packers +240
    • Total
      42.5

The Kansas City Chiefs are just 7-11 ATS following a win since the start of 2022.

Overs are 8-3 following the Green Bay Packers’ past 11 wins.

Cincinnati Bengals vs. Jacksonville Jaguars Odds

    • Spread
      Jaguars -8.5
    • Moneyline
      Bengals +310, Jaguars -390
    • Total
      38.5

Unders are 5-2 since the beginning of last season when Cincinnati is getting points.

Both the Jacksonville Jaguars and Bengals have been top-10 teams since the beginning of 2021 in hitting the under (JAX: 59.6%, CIN: 60%).

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