The Arizona Cardinals will host the San Francisco 49ers in Week 11. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, specifically regarding QB Kyler Murray.

Is Kyler Murray Playing in Week 11?
Murray, who was placed on injured reserve on Wednesday due to a mid-foot sprain, is not expected to start again if he returns this season, absent injury to Jacoby Brissett, Ian Rapoport of NFL Network reports.
We’ll continue to monitor the Cardinals’ injury report leading up to kickoff for any changes. You can also visit and bookmark our Fantasy News Tracker for the latest updates.
Should You Start or Sit Murray in Week 11?
The fact that we needed reports two weeks ago to tell us that the Cardinals’ starting Brissett was “not some kind of benching” of Murray is a concern.
The foot injury is a worry for a player who, at the peak of his powers, threatens defenses in a multitude of ways, but even pre-injury, we are talking about a quarterback who has yet to post a top-12 finish at the position this season.
Murray is pacing for a career low in both fantasy points per pass and per rush, making him a tough sell until we have a clean bill of health, and even then, I think I’d need to see it on the field before trusting him in lineups.
With the IR tag slapped on him last Wednesday, Murray will miss the remainder of the month, with a return in Week 14 his next possible opportunity to impact our world.
The Cardinals play the Rams and Texans in Weeks 14-15, two matchups that I’d rather not touch, and that means, at best, a Week 16 home game against the Falcons is the next time you’d feel even remotely confident in considering Murray.
Jacoby Brissett needed garbage time last week, but he has this offense functioning at a higher level, and that could mean that Murray has already taken his final snap of 2022.
You can move on.
Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.
Murray’s Fantasy Points Projection in Week 11
Murray is projected to score 0.0 points in PPR formats. This includes 0.0 receptions for 0.0 yards and 0.0 touchdowns.
Check out the free PFSN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.
Week 11 Weather Impact: 49ers at Cardinals
Since the Cardinals play in a dome, there is no weather impact for this Week 11 matchup. Temperatures will be a comfortable 72 degrees Fahrenheit with no wind.
