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    Week 5 Fantasy WR Rankings: Start-Sit Advice for Jerry Jeudy, Jordan Addison, Justin Jefferson, and Others

    Week 5 of the fantasy football season has arrived, and it’s more important than ever to know which players deserve a place in your starting lineup. Considering player talent, recent form, and matchups, we’ve put together our PFSN consensus Week 5 WR rankings.

    These rankings were last updated at 8:00 AM ET on Thursday, October 05, 2025.

    Check out the FREE Start/Sit Optimizer from PFSN to ensure you are making the right decisions for your fantasy lineup every week!
    Check out the FREE Start/Sit Optimizer from PFSN to ensure you are making the right decisions for your fantasy lineup every week!

    Week 5 WR Fantasy Rankings

    1) Puka Nacua | Los Angeles Rams (vs. SF)
    2) Amon-Ra St. Brown | Detroit Lions (at CIN)
    3) Jaxon Smith-Njigba | Seattle Seahawks (vs. TB)
    4) Garrett Wilson | New York Jets (vs. DAL)
    5) Nico Collins | Houston Texans (at BAL)
    6) Ja’Marr Chase | Cincinnati Bengals (vs. DET)
    7) Justin Jefferson | Minnesota Vikings (vs. CLE (London))
    8) George Pickens | Dallas Cowboys (at NYJ)
    9) Davante Adams | Los Angeles Rams (vs. SF)
    10) Zay Flowers | Baltimore Ravens (vs. HOU)
    11) Xavier Worthy | Kansas City Chiefs (at JAX)
    12) Quentin Johnston | Los Angeles Chargers (vs. WAS)
    13) Emeka Egbuka | Tampa Bay Buccaneers (at SEA)
    14) Deebo Samuel Sr. | Washington Commanders (at LAC)
    15) A.J. Brown | Philadelphia Eagles (vs. DEN)
    16) Courtland Sutton | Denver Broncos (at PHI)
    17) Tetairoa McMillan | Carolina Panthers (vs. MIA)
    18) Michael Pittman Jr. | Indianapolis Colts (vs. LV)
    19) Keenan Allen | Los Angeles Chargers (vs. WAS)
    20) Chris Olave | New Orleans Saints (vs. NYG)
    21) Jakobi Meyers | Las Vegas Raiders (at IND)
    22) Marvin Harrison Jr. | Arizona Cardinals (vs. TEN)
    23) Chris Godwin | Tampa Bay Buccaneers (at SEA)
    24) Brian Thomas Jr. | Jacksonville Jaguars (vs. KC)
    25) Ladd McConkey | Los Angeles Chargers (vs. WAS)
    26) Jameson Williams | Detroit Lions (at CIN)
    27) DeVonta Smith | Philadelphia Eagles (vs. DEN)
    28) Tee Higgins | Cincinnati Bengals (vs. DET)
    29) Jordan Addison | Minnesota Vikings (vs. CLE (London))
    30) Jaylen Waddle | Miami Dolphins (at CAR)
    31) Stefon Diggs | New England Patriots (at BUF)
    32) Keon Coleman | Buffalo Bills (vs. NE)
    33) Wan’Dale Robinson | New York Giants (at NO)
    34) Khalil Shakir | Buffalo Bills (vs. NE)
    35) Jerry Jeudy | Cleveland Browns (vs. MIN (London))
    36) Calvin Ridley | Tennessee Titans (at ARI)
    37) Troy Franklin | Denver Broncos (at PHI)
    38) Rashid Shaheed | New Orleans Saints (vs. NYG)
    39) Elic Ayomanor | Tennessee Titans (at ARI)
    40) Travis Hunter | Jacksonville Jaguars (vs. KC)
    41) Darius Slayton | New York Giants (at NO)
    42) Cooper Kupp | Seattle Seahawks (vs. TB)
    43) Christian Kirk | Houston Texans (at BAL)
    44) Tre Tucker | Las Vegas Raiders (at IND)
    45) Josh Downs | Indianapolis Colts (vs. LV)
    46) Kendrick Bourne | San Francisco 49ers (at LAR)
    47) Kayshon Boutte | New England Patriots (at BUF)
    48) Sterling Shepard | Tampa Bay Buccaneers (at SEA)
    49) Hollywood Brown | Kansas City Chiefs (at JAX)
    50) Tyquan Thornton | Kansas City Chiefs (at JAX)

    Jameson Williams, WR, Detroit Lions

    Jameson Williams was tipped by many for a big year in 2025, but has started the season with three fantasy finishes outside the top 50 wide receivers in the opening four weeks. Against Cleveland in Week 4, Williams caught two passes for 40 yards, but he was targeted eight times.

    Many of those targets were deep balls and potential walk-in touchdowns, but Jared Goff could not connect. Williams remains a big-play threat, and the Detroit Lions will look to get him going in the coming weeks.

    Having started slowly, the Lions have scored 116 points in their last three games, and Williams’s eight targets clearly indicate that Detroit wants him involved. The electric deep threat was the WR22 overall last season and should be available at a huge discount this week.

    Demarcus Robinson, WR, 49ers

    Demarcus Robinson earned two targets in his 2025 debut and is going to be relied on more heavily tonight due to the injuries around him.

    The quality of those looks is in question with Mac Jones actually taking over for Brock Purdy (toe), but there is YOLO upside to chase if you’re desperate.

    In this revenge game, Robinson could turn one target into 8-10 fantasy points. The 49ers are a big underdog in this spot, and he was running vertical for the majority of last season (16.6 aDOT).

    I’m going out of my way to NOT throw darts at this situation, but if I had to gamble on one to make a splash play, Robinson is it.

    Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.

    Should You Start or Sit Puka Nacua in Week 5?

    Evolution is nice, but mankind is unequipped to deal with some things and that’s just the way it is.

    We couldn’t stop the avocado toast momentum, and traffic at rush hour remains undefeated. I think I’m ready to add “guarding Puka Nacua” to that list.

    We are four weeks into the season, and the Los Angeles star has three games with 9+ targets and an 85%+ catch rate. We haven’t seen a receiver go over that number for an entire season since Michael Thomas in 2019 (five), and the NFL has shown no ability to quiet everything he does well.

    Chris Olave is the only player in the league with as many targets as Nacua has receptions, and given the efficiency of those looks, I’d question the Rams if they didn’t keep peppering him with looks all over the field.

    Remember when Nacua initially established himself as a star? He had a big Week 1 to open his career, but it was the second week that showed stability to what he was doing.

    That was a 15-catch, 20-target performance against the 49ers.

    I’m not projecting that this week, but would it shock you to see him repeat?

    Should You Start or Sit Jeudy in Week 5?

    With Cedric Tillman out for this week and likely more, you’re probably going to have to get comfortable at least considering Jeudy as a top 30 receiver.

    The numbers haven’t been there yet (13 catches in four games with zero games of 70+ yards), but with 8+ targets and a 25+ yard catch in three of four games, there are some signs that he could be nearing his best week of the season.

    Starting next week.

    In 2024, 29.7% of his targets came deep downfield, but that rate has spiked to 43.3% through four weeks this season. That’s great in spots where the home run ball is available, but opponents have the second-lowest aDOT against the Vikings this season, which will make accessing a ceiling game difficult.

    The Browns get the Steelers and Dolphins in Weeks 6-7, two of the five worst pass defenses in the league. I think you sit Jeudy this week, maybe even buy low, with the hope that the breakout isn’t far away.

    Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.

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