Week 6 of the fantasy football season has arrived, and it’s more important than ever to know which players deserve a place in your starting lineup. Considering player talent, recent form, and matchups, we’ve put together our PFSN consensus Week 6 RB rankings.
These rankings were last updated at 8:00 AM ET on Thursday, October 09, 2025.
Week 6 RB Fantasy Rankings
1) Christian McCaffrey | San Francisco 49ers (at TB)
2) Bijan Robinson | Atlanta Falcons (vs. BUF)
3) Jahmyr Gibbs | Detroit Lions (at KC)
4) Jonathan Taylor | Indianapolis Colts (vs. ARI)
5) Saquon Barkley | Philadelphia Eagles (at NYG)
6) Josh Jacobs | Green Bay Packers (vs. CIN)
7) James Cook | Buffalo Bills (at ATL)
8) De’Von Achane | Miami Dolphins (vs. LAC)
9) Javonte Williams | Dallas Cowboys (at CAR)
10) Kyren Williams | Los Angeles Rams (at BAL)
11) Ashton Jeanty | Las Vegas Raiders (vs. TEN)
12) Derrick Henry | Baltimore Ravens (vs. LAR)
13) Rico Dowdle | Carolina Panthers (vs. DAL)
14) Quinshon Judkins | Cleveland Browns (at PIT)
15) Breece Hall | New York Jets (vs. DEN)
16) J.K. Dobbins | Denver Broncos (at NYJ)
17) Jacory Croskey-Merritt | Washington Commanders (vs. CHI)
18) Cam Skattebo | New York Giants (vs. PHI)
19) Rachaad White | Tampa Bay Buccaneers (vs. SF)
20) Alvin Kamara | New Orleans Saints (vs. NE)
21) Travis Etienne Jr. | Jacksonville Jaguars (vs. SEA)
22) Tony Pollard | Tennessee Titans (at LV)
23) D’Andre Swift | Chicago Bears (at WAS)
24) David Montgomery | Detroit Lions (at KC)
25) Rhamondre Stevenson | New England Patriots (at NO)
26) Jaylen Warren | Pittsburgh Steelers (vs. CLE)
27) Michael Carter | Arizona Cardinals (at IND)
28) Zach Charbonnet | Seattle Seahawks (at JAX)
29) Kenneth Walker III | Seattle Seahawks (at JAX)
30) Chase Brown | Cincinnati Bengals (at GB)
31) TreVeyon Henderson | New England Patriots (at NO)
32) Kenneth Gainwell | Pittsburgh Steelers (vs. CLE)
33) Kendre Miller | New Orleans Saints (vs. NE)
34) Justice Hill | Baltimore Ravens (vs. LAR)
35) Tyler Allgeier | Atlanta Falcons (vs. BUF)
36) Kareem Hunt | Kansas City Chiefs (vs. DET)
37) RJ Harvey | Denver Broncos (at NYJ)
38) Isiah Pacheco | Kansas City Chiefs (vs. DET)
39) Kimani Vidal | Los Angeles Chargers (at MIA)
40) Hassan Haskins | Los Angeles Chargers (at MIA)
41) Tyrone Tracy Jr. | New York Giants (vs. PHI)
42) Isaiah Davis | New York Jets (vs. DEN)
43) Bhayshul Tuten | Jacksonville Jaguars (vs. SEA)
44) Brashard Smith | Kansas City Chiefs (vs. DET)
45) Emari Demercado | Arizona Cardinals (at IND)
46) Blake Corum | Los Angeles Rams (at BAL)
47) Chris Rodriguez Jr. | Washington Commanders (vs. CHI)
48) Ollie Gordon II | Miami Dolphins (vs. LAC)
49) Sean Tucker | Tampa Bay Buccaneers (vs. SF)
50) Tyjae Spears | Tennessee Titans (at LV)
Chase Brown, RB, Cincinnati Bengals
Like Henry, Cincinnati Bengals running back Chase Brown has been an enormous disappointment in fantasy this year. The entire Bengals offense has struggled following Joe Burrow’s Week 2 injury, with backup Jake Browning looking well below par.
Having won their opening two games of the season, the Bengals can still make the playoffs, despite their recent slump. After a considerable investment in their offensive weapons this past offseason, they can’t afford to be idle.
Browning got the offense moving late against the Detroit Lions in Week 5, but the entire second half felt like garbage time, given how poorly the Bengals were playing. Cincinnati needs to find a way to get Brown more involved, and if you can get him for mid to low-end RB2 value, he’s talented enough to bet on.
TreVeyon Henderson, RB, New England Patriots
It’s only a matter of time until TreVeyon Henderson gets a real opportunity to blow up in fantasy football. Currently, it seems that, regardless of how many times he fumbles the ball, Rhamondre Stevenson will continue to receive the best opportunities for the New England Patriots.
However, that won’t last forever, and Henderson is explosive enough to force the team to feed him sooner or later. It’s not unusual for rookies to be introduced slowly, and nobody should be panicking about the former Ohio State star just yet.
Antonio Gibson left Week 5’s game against the Buffalo Bills with a knee injury, which could help Henderson’s cause moving forward. Upcoming games against the New Orleans Saints and Tennessee Titans should offer the rookie an excellent opportunity to earn a starting role.
Henderson should be pursued at a mid-to-low-end RB2 value, and will be a weekly RB1 contender when he finally takes over in New England.
Cam Skattebo | NYG (vs PHI)
It doesn’t have to be complicated.
Cam Skattebo runs as hard as anyone, has holes open up thanks to a versatile QB, and has soft hands (18 catches on 22 targets this season).
I understand that this offensive environment isn’t as friendly as most, but it’s a concentrated unit that prioritizes giving its young pieces valuable reps.
This is a difficult matchup, and while efficiency could be an issue, I’m not worried about the bottom line. Skattebo is a script-proof back, and that’s going to land him safely inside of my top 20 every single week moving forward.
Chase Brown | CIN (at GB)
Chase Brown can’t win, even when the Bengals are down so bad that all other fantasy options get home.
In a Week 5 dismantling at the hands of the Lions that saw Chase finish as the WR2 for the week and Tee Higgins get into the end zone with a meaningless score, Brown was still unable to post his first top-20 finish of the season.
Man, this has been brutal. He’s averaging 2.5 yards and only has two red zone touches over the past three weeks. His fluidity in the pass game is the lone saving grace, but that means putting your weekly fate in the hands of this QB situation, and that’s just not comfortable.
I’d love to sell you hope. I was high on Brown entering the season, and skill set-wise, I stand by it, but he’s nothing more than a risky flex these days. In four of five games, the lack of support has resulted in him coming up more than 20% shy of fantasy expectations based on his touch type, a trend that I have a hard time thinking the course corrects.
And now he gets a talented Packers defense off a bye?
I’d rather my week rely on the bizarre usage of the New England running backs or speculate on Hassan Haskins getting the bulk of the work in the first week of Omarion Hampton’s stay on IR.
With the Bengals moving to Flacco, the offensive integrity rises, even without proof of concept. Brown slides into the back-end of my RB2 tier.