The San Francisco 49ers will visit the Arizona Cardinals in Week 11. Here’s the latest fantasy football news and advice to help you with your lineups this week and moving forward, specifically regarding RB Christian McCaffrey.

Is Christian McCaffrey Playing in Week 11?
McCaffrey is not on the injury report, and barring a surprise, he is expected to play.
We’ll continue to monitor the 49ers’ injury report leading up to kickoff for any changes. You can also visit and bookmark our Fantasy News Tracker for the latest updates.
Should You Start or Sit McCaffrey in Week 11?
Christian McCaffrey is a workhorse running back who is averaging a target for every two rush attempts this season.
He has 69 catches and 180 carries this season; no other running back with 145+ carries has more than 32 targets.
We are dealing with a truly unique player with the highest floor we’ve seen in quite some time. McCaffrey is averaging 3.5 yards per carry and doesn’t have a run gaining more than 16 yards; it doesn’t matter.
The Brian Robinson drive last week (the first of the second half) was a pain, but your complaining is going to fall on deaf ears. You got a discount on the most fantasy-friendly role of a generation: it’s on you to build a winner around him.
The 49ers get the Titans, Colts, and Bears during the fantasy postseason. CMC is going to do his job; you can count on that.
Are you looking for start/sit advice for other players in your lineup? Read our Fantasy Football Start ‘Em, Sit ‘Em Cheat Sheet.
McCaffrey’s Fantasy Points Projection in Week 11
McCaffrey is projected to score 25.4 fantasy points in PPR formats.
We project McCaffrey to rush for 91 yards and 0.5 rushing touchdowns, while adding 6 receptions for 55 receiving yards and 0.3 receiving touchdowns.
Check out the free PFSN Fantasy Start-Sit Optimizer for the latest projections and advice for your lineups this week.
Week 11 Weather Impact: 49ers at Cardinals
Since the Cardinals play in a dome, there is no weather impact for this Week 11 matchup. Temperatures will be a comfortable 72 degrees Fahrenheit with no wind.
