49ers vs. Jaguars prediction, pick, odds, and how to watch the Week 11 game

What is our prediction for the 49ers vs. Jaguars Week 11 matchup, what channel is the game on, and what are the betting odds?

The volatile performances of these teams have made making a prediction for this San Francisco 49ers vs. Jacksonville Jaguars matchup tough to make for Week 11. Let’s take a look at the adventure so far in 2021 for these two teams, the NFL odds, make a prediction for the outcome, and look at what channel/station you can watch/listen to this 49ers at Jaguars clash.

San Francisco 49ers vs. Jacksonville Jaguars prediction and odds | Week 11

  • Spread: 49ers -6.5 (Odds from DraftKings sportsbook)
  • Moneyline: 49ers -275, Jaguars +220
  • Over/Under: 45

The 49ers’ victory over the Rams on Monday Night Football was almost as shocking as the Jaguars’ victory over the Buffalo Bills the week before. Given the 49ers came into that game having won just one of their last six, not many gave them hope, but they produced a complete performance to stun one of the NFC favorites.

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It was just the third time the 49ers had covered against the spread (ATS) in a game this year — their defense was a big reason why. Having given up an average of 27.7 points per game across their previous three games, holding the Rams to just 10 points was impressive. However, the circumstances are somewhat different here with the 49ers favored. As favorites this year, San Francisco is just 2-5 ATS.

The Jaguars have certainly turned the narrative surrounding them around. They have covered ATS in three of the last four and have gone 2-2 straight up in that time period. Consistency has been their issue, but Jacksonville’s two recent defensive performances offer hope. In terms of the total, the under has hit in all of the Jaguars’ last four games and seven of nine this season.

49ers vs. Jaguars prediction

The problem with the 49ers is that we have no idea if we will see the team that lost 30-18 to the Colts in Week 6 or the team that steamrolled the Rams last week. The answer is somewhere in the middle, but their defensive performances are tough to predict. There likely has to be some regression from last week, but that will be mitigated by the struggles of the Jaguars’ offense.

The Jaguars’ defense has equally been impressive recently. Shutting down the Bills’ offense and then keeping the Colts under wraps should not be underestimated. Their defense should keep this game relatively low scoring, it just falls on the offense to make that count. The Jaguars have a great chance to cover if the offense does not commit costly turnovers, and the under is very much in play.

49ers vs. Jaguars Prediction: 49ers 23, Jaguars 20

How to watch and listen to 49ers vs. Jaguars this week

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